Dagmar Roth
University of Liverpool
7 Papers
238 Citations
Dagmar Roth is an academic researcher from University of Liverpool. The author has contributed to research in topics: Exocytosis & Adrenal medulla. The author has an hindex of 7, co-authored 7 publications.
Chat about Author
Papers
Stimulation of catecholamine secretion from adrenal chromaffin cells by 14-3-3 proteins is due to reorganisation of the cortical actin network
Dagmar Roth,Robert D. Burgoyne +1 more
TL;DR: It is suggested that 14‐3‐3 proteins enhance catecholamine release in permeabilized chromaffin cells by reorganisation of the cortical actin barrier to allow increased availability of secretory vesicles for exocytosis.
78
Identification of a key domain in annexin and 14-3-3 proteins that stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cells
TL;DR: The data suggest that the shared annexin/14‐3‐3 domain is important in the mechanisms controlling Ca2+‐dependent secretion and may play a key role in protein‐protein interactions during exocytosis.
67
Characterization of 14-3-3 proteins in adrenal chromaffin cells and demonstration of isoform-specific phospholipid binding.
Dagmar Roth,Alan Morgan,Harry Martin,David T. Jones,G J M Martens,Alastair Aitken,Robert D. Burgoyne +6 more
TL;DR: Recombinant 14-3-3 isoforms were able to stimulate Ca(2+)-dependent exocytosis in digitonin-permeabilized chromaffin cells, and the Xenopus proteins lacks part of the extreme N-terminus, indicating that this domain is not essential for function in exocyTosis.
Identification of cytosolic protein regulators of exocytosis
TL;DR: 32. Hochner, H., I�’arnas, H. and I’ Carnas, 1.
21
Characterization of Proteins That Regulate Calcium‐dependent Exocytosis in Adrenal Chromaffin Cells
TL;DR: The identification and characterization of soluble proteins, which have been identified to date, that stimulate Ca2+ -dependent exocytosis in a run-down reconstitution assay and the possible role of GTP-binding proteins in exocyTosis in digitoqin-permeabilized chromaffin cells are described.
16