70 Papers
814 Citations
Dae Yeul Yu is an academic researcher from Korea Research Institute of Bioscience and Biotechnology. The author has contributed to research in topics: Peroxiredoxin & Gene. The author has an hindex of 28, co-authored 70 publications. Previous affiliations of Dae Yeul Yu include Korea University of Science and Technology.
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Papers
Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice
Tae Hoon Lee,Sun Uk Kim,Seong Lan Yu,Sue Hee Kim,Do-Sim Park,Hyung Moon,So Hee Dho,Ki Sun Kwon,Hyun Jeong Kwon,Ying Hao Han,Sangkyun Jeong,Sang Won Kang,Hee Sup Shin,Kyung Kwang Lee,Sue Goo Rhee,Dae Yeul Yu +15 more
TL;DR: The results suggest that Prx II-/- mice have hemolytic anemia and that PrX II plays a major role in protecting RBCs from oxidative stress in mice.
423
Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARγ
Kook Hwan Kim,Hye Jun Shin,Kyeong Jin Kim,Hyun Mi Choi,Sang Hoon Rhee,Hyung Moon,Hyeong Hoe Kim,Ung Suk Yang,Dae Yeul Yu,JaeHun Cheong +9 more
TL;DR: It is shown that the increased HBx expression causes lipid accumulation in hepatic cells mediated by sterol regulatory element binding protein 1 and PPARγ, which could be a putative molecular mechanism mediating the pathophysiology of HBV infection.
274
Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein.
Dae Yeul Yu,Hyung Moon,Jin Kyong Son,Sang Kyun Jeong,Seong Lan Yu,Hee Sik Yoon,Yong Mahn Han,Chul Sang Lee,Jung Sun Park,Chul-Ho Lee,Byung Hwa Hyun,Seishi Murakami,Kyung Kwang Lee +12 more
TL;DR: The incidence of hepatocellular carcinoma (86%) in the HBV X transgenic mice produced in other laboratories did not develop liver tumor or any other pathologic phenomena, which may be highly significant.
246
Human Hepatitis B Virus-X Protein Alters Mitochondrial Function and Physiology in Human Liver Cells
Young Ik Lee,Jung Me Hwang,Jee Hye Im,Yoon Ik Lee,Nam Soon Kim,Dae Gon Kim,Dae Yeul Yu,Hyung Moon,Sook Kyung Park +8 more
TL;DR: It is concluded that mitochondrial dysfunction is a crucial pathophysiological factor in HBx-expressing hepatoma cells and provides an experimental rationale in the investigation of mitochondrial function in rapidly renewed tissues, as in hepatocellular carcinomas.
170
•Journal Article
Overexpression of Membrane-type Matrix Metalloproteinase-1 Gene Induces Mammary Gland Abnormalities and Adenocarcinoma in Transgenic Mice
Hye Yeong Ha,Hyung Moon,Myoung Soo Nam,Jeong Woong Lee,Zae Yoong Ryoo,Tae-Hoon Lee,Kyung Kwang Lee,Byung Jan So,Hiroshi Sato,Motoharu Seiki,Dae Yeul Yu +10 more
TL;DR: It is suggested that overexpression of MT1-MMP may play a key role in development and tumorigenesis in mammary glands and Gelatin zymography showed significantly increased MMP-2 activation in these Mammary glands.
150