Daan Noordermeer
Université Paris-Saclay
6 Papers
11 Citations
Daan Noordermeer is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Chromatin & Heterochromatin. The author has an hindex of 3, co-authored 6 publications.
Chat about Author
Papers
Loss of EZH2-like or SU(VAR)3–9-like proteins causes simultaneous perturbations in H3K27 and H3K9 tri-methylation and associated developmental defects in the fungus Podospora anserina
F. Carlier,F. Carlier,M. Li,L. Maroc,Robert Debuchy,C. Souaid,C. Souaid,Daan Noordermeer,Pierre Grognet,Fabienne Malagnac +9 more
TL;DR: In this paper, the authors exploited the fungus Podospora anserina, a valuable alternative to higher eukaryote models, to question the biological relevance and functional interplay of these two distinct heterochromatin conformations.
Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency.
Maxim Van Cleef Greenberg,Aurélie Teissandier,Marius Walter,Daan Noordermeer,Déborah Bourc'his +4 more
TL;DR: It is shown that 3D regulation occurs upstream of the polycomb and DNA methylation pathways, and the importance of multi-layered regulatory frameworks to ensure proper spatio-temporal activation of developmentally important genes is revealed.
15
Loop extrusion as a mechanism for DNA Double-Strand Breaks repair foci formation
Coline Arnould,Rocher,Thomas Clouaire,Pierre Caron,Philippe E. Mangeot,Emiliano P. Ricci,Raphaël Mourad,Daan Noordermeer,Gaëlle Legube +8 more
TL;DR: This work highlights the critical impact of chromosome conformation in the maintenance of genome integrity and provides the first example of a chromatin modification established by loop extrusion.
Loss of Polycomb Protein EZH2 causes major depletion of H3K27 and H3K9 tri-methylation and developmental defects in the fungus Podospora anserina
F. Carlier,F. Carlier,Robert Debuchy,L. Maroc,C. Souaid,C. Souaid,Daan Noordermeer,Pierre Grognet,Fabienne Malagnac +8 more
TL;DR: It is established that P. anserina developmental programs require H3K27me3 mediated silencing unlike most fungi studied to date, and new insight is provided into roles of these histone marks and into the relationship between chromatin modifications and development.
A fast Myh super enhancer dictates adult muscle fiber phenotype through competitive interactions with the fast Myh genes
Santos,Stéphanie Backer,Frédéric Auradé,Frédéric Auradé,Wong M,Maud Wurmser,Pierre R,Francina Langa,Cruzeiro,Alain Schmitt,Jean-Paul Concordet,Athanassia Sotiropoulos,Jeffrey Dilworth,Daan Noordermeer,Frédéric Relaix,Sakakibara I,Sakakibara I,Pascal Maire +17 more
TL;DR: In this article, the authors identify a 42kb super-enhancer (SE) at the locus regrouping the fast Myosin heavy chain (myH) genes.
1