D. Srinivas
Dr. Reddy's Laboratories
14 Papers
76 Citations
D. Srinivas is an academic researcher from Dr. Reddy's Laboratories. The author has contributed to research in topics: Chemistry & Thiocarbamate. The author has an hindex of 8, co-authored 14 publications. Previous affiliations of D. Srinivas include National Chemical Laboratory.
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Papers
Synthesis of conformationally constrained analogues of linezolid: structure-activity relationship (SAR) studies on selected novel tricyclic oxazolidinones.
N. Selvakumar,D. Srinivas,Manoj Kumar Khera,Magadi Sitaram Kumar,Rao N. V. S. Mamidi,Hemanth Sarnaik,Chandrashekar Charavaryamath,B. S. Rao,Mohammed A. Raheem,Jagattaran Das,Javed Iqbal,Ramanujam Rajagopalan +11 more
TL;DR: In an effort to discover potent antibacterials based on the entropically favored "bioactive conformation" approach, a series of novel tricyclic molecules mimicking the conformationally constrained structure of the oxazolidinone antibacterial, Linezolid 1 are designed and synthesized.
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A direct synthesis of 2-arylpropenoic acid esters having nitro groups in the aromatic ring: a short synthesis of (±)-coerulescine and (±)-horsfiline †
TL;DR: In this article, a short synthesis of 2-arylpropenoic acid esters that possess nitro groups in their phenyl ring using common and less expensive reagents is described.
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An efficient total synthesis of 9-methoxycarbazole-3-carbaldehyde based on a novel methodology for the preparation of methoxyindoles
TL;DR: In this article, the synthesis of 9-methoxycarbazole-3-carbaldehyde using ring closing metathesis has been reported in seven steps in 14% overall yield from commercial materials and in only four steps from a methoxyindole compound obtained using the new methodology.
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Synthesis of novel tricyclic oxazolidinones by a tandem SN2 and SNAr reaction: SAR studies on conformationally constrained analogues of Linezolid.
N. Selvakumar,B. Yadi Reddy,G. Sunil Kumar,Manoj Kumar Khera,D. Srinivas,M. Sitaram Kumar,Jagattaran Das,Javed Iqbal,Sanjay Trehan +8 more
TL;DR: A series of conformationally constrained analogues of Linezolid were synthesised by employing a tandem SN(2) and SNAr reaction as the key step and tested for antibacterial activity, where the tetrahydroazolo-benzothiazine compounds exhibited interesting antib bacterial activity.
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Observation of O→N Type Smiles Rearrangement in Certain Alkyl Aryl Nitro Compounds
TL;DR: Smiles rearrangements on some alkyl aryl nitro compounds having NH 2 group as the nucleophile and oxygen as the leaving group are reported in this article.
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