D. Perrone
University of Foggia
14 Papers
54 Citations
D. Perrone is an academic researcher from University of Foggia. The author has contributed to research in topics: Cancer & Curcumin. The author has an hindex of 9, co-authored 14 publications.
Chat about Author
Papers
The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review)
TL;DR: The mechanism of action of phosphorylation is discussed, with particular attention to the importance ofosphorylation under physiological and pathological conditions, and the possibility of using kinase inhibitors in the treatment of tumors.
Biological and therapeutic activities, and anticancer properties of curcumin (Review)
D. Perrone,Fatima Ardito,G Giannatempo,Mario Dioguardi,Giuseppe Troiano,Lucio Lo Russo,Alfredo De Lillo,Luigi Laino,Lorenzo Lo Muzio +8 more
TL;DR: All the studies reviewed herein suggest that curcumin is able to exert anti-inflammatory, antiplatelet, antioxidative, hepatoprotective and antitumor activities, particularly against cancers of the liver, skin, pancreas, prostate, ovary, lung and head neck, as well as having a positive effect in the treatment of arthritis.
Resveratrol (3,5,4'-trihydroxystilbene) and its properties in oral diseases (Review)
D. Perrone,Maria Pia Fuggetta,Fatima Ardito,Andrea Cottarelli,Anna De Filippis,Giampietro Ravagnan,Salvatore De Maria,Lorenzo Lo Muzio +7 more
TL;DR: Considering its multiple properties, the present review has focused on the potential benefits of RSV as an antioxidant and chemopreventive agent.
Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment.
Vitalba Ruggieri,Francesca Agriesti,Rosella Scrima,Ilaria Laurenzana,D. Perrone,Tiziana Tataranni,Carmela Mazzoccoli,Lorenzo Lo Muzio,Nazzareno Capitanio,Claudia Piccoli +9 more
TL;DR: The data here presented indicate that the therapeutic efficacy of DCA may depend on the specific metabolic profile adopted by the cancer cells with those exhibiting a deficient mitochondrial oxidative phosphorylation resulting more sensitive to the drug treatment.
In vitro evaluation of the cytotoxic activity of three epoxy resin-based endodontic sealers.
Giuseppe Troiano,D. Perrone,Mario Dioguardi,Alessio Buonavoglia,Fatima Ardito,Lorenzo Lo Muzio +5 more
TL;DR: All the three epoxy resin-based sealers showed a medium rate of cytotoxicity on osteoblasts-like cells in vitro, and no significant difference was found among the sealers analyzed.
30