D. Lagarde
Paris Descartes University
26 Papers
316 Citations
D. Lagarde is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Sleep deprivation & Modafinil. The author has an hindex of 13, co-authored 25 publications.
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Papers
Interest of modafinil, a new psychostimulant, during a sixty-hour sleep deprivation experiment
TL;DR: The confirmed wakening potency of modafinil makes this substance suitable for therapeutic use in patients with sleep disorders such as Gelineau's syndrome and hypersomnia.
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Resynchronization of hormonal rhythms after an eastbound flight in humans: effects of slow-release caffeine and melatonin.
Christophe Piérard,Maurice Beaumont,Marc Enslen,Françoise Chauffard,Dux-Xian Tan,Russel J. Reiter,Annick Fontan,Jonathan French,Olivier Coste,D. Lagarde +9 more
TL;DR: Results indicate that administration of slow-release caffeine, as well as of melatonin, allows a faster resynchronization of hormone rhythms during the 4 days following an eastbound flight incurring a time loss of 7 h.
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Slow-release caffeine: a new response to the effects of a limited sleep deprivation.
D. Lagarde,Denise Batéjat,Bruno Sicard,Suzanne Trocherie,Didier Chassard,Marc Enslen,Françoise Chauffard +6 more
TL;DR: SR caffeine (300 mg) seems to be an efficient and safety substance to maintain a good level of vigilance and performance during limited sleep deprivation.
Electroencephalographic effects of modafinil, an alpha-1-adrenergic psychostimulant, on the sleep of rhesus monkeys.
D. Lagarde,Claude Milhaud +1 more
TL;DR: Modafinil has a wakening effect at the dose of 6mg/kg in rhesus monkeys and induces quasicontinuous wakefulness for 4 total days and nights with daily administration of 22.5 mg/kg, with no behavioral disorders, and should find interesting applications in sleep disorder treatments.
Recovery after Prolonged Sleep Deprivation: Residual Effects of Slow-Release Caffeine on Recovery Sleep, Sleepiness and Cognitive Functions
Maurice Beaumont,Denise Batéjat,Olivier Coste,Philippe Doireau,Françoise Chauffard,Marc Enslen,D. Lagarde,Christophe Piérard +7 more
TL;DR: SRC appears to have no unwanted side-effects on recovery sleep, wakefulness and cognitive performance after a long period of sleep deprivation and might therefore be a useful choice over other psychostimulants for a long work schedule.
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