Cyrille Boyer
University of New South Wales
424 Papers
2.7K Citations
Cyrille Boyer is an academic researcher from University of New South Wales. The author has contributed to research in topics: Polymerization & Chain transfer. The author has an hindex of 87, co-authored 379 publications. Previous affiliations of Cyrille Boyer include Centre national de la recherche scientifique & Dow Chemical Company.
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Papers
A Rationally Optimized Nanoparticle System for the Delivery of RNA Interference Therapeutics into Pancreatic Tumors in Vivo
Joann Teo,Joshua A. McCarroll,Cyrille Boyer,Janet Youkhana,Sharon M. Sagnella,Hien T. T. Duong,Jie Liu,George Sharbeen,David Goldstein,Thomas P. Davis,Thomas P. Davis,Maria Kavallaris,Phoebe A. Phillips +12 more
TL;DR: The synthesis and physicochemical characterization of star polymers are described using reversible addition-fragmentation chain transfer polymerization (RAFT) for the delivery of siRNA to pancreatic cancer cells and it is shown that star-POEGMA polymers could readily self-assemble with si RNA to form nanoparticles.
In Vitro Cytotoxicity of RAFT Polymers
TL;DR: In this study, the in vitro cytotoxicity of three different, RAFT-synthesized, water-soluble polymers was investigated using three different adherent cell lines via CellTiter-Blue cell viability and the cytosolic enzyme lactate dehydrogenase (LDH) cytot toxicity assays.
Acid Degradable and Biocompatible Polymeric Nanoparticles for the Potential Codelivery of Therapeutic Agents
TL;DR: The synthesis of well-defined functional nanoparticles for the encapsulation of hydrophobic and hydrophilic drugs is described and a cross-linker bearing an acid cleavable bond (ketal) was used to generate pH-sensitive core–shell nanoparticles.
Synthesis of Light-Responsive Pyrene-Based Polymer Nanoparticles via Polymerization-Induced Self-Assembly.
TL;DR: The UV-light-induced dissociation of these light-responsive nanoparticles due to the gradual cleavage of the pyrene moieties and the subsequent hydrophobic-to-hydrophilic transitions of the core-forming blocks is demonstrated.
Effect of hydrophilic groups on the bioactivity of antimicrobial polymers
TL;DR: In this article, the effect of hydrophilic groups on antibacterial activity and biocompatibility was investigated using a series of statistical amphiphilic ternary polymers and the results revealed that, unlike the hydrophobic groups that directly disrupt the cell membrane, the hydophilic groups have an indirect but important impact on bioactivity through tuning of the hydphobic/hydrophilic balance and global hydrophobicity, leading to a change in the aqueous characteristics of the polymers.