Cynthia E Chico
Emory University
6 Papers
Cynthia E Chico is an academic researcher from Emory University. The author has contributed to research in topics: Cancer & DNA methylation. The author has an hindex of 4, co-authored 6 publications.
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Papers
Epigenetic age acceleration, fatigue, and inflammation in patients undergoing radiation therapy for head and neck cancer: A longitudinal study
Canhua Xiao,Jonathan J. Beitler,Gang Peng,Morgan E. Levine,Karen N. Conneely,Hongyu Zhao,Jennifer C. Felger,Evanthia C. Wommack,Cynthia E Chico,Sangchoon Jeon,Kristin Higgins,Dong M. Shin,Nabil F. Saba,Barbara Burtness,Deborah Watkins Bruner,Andrew H. Miller +15 more
TL;DR: In this paper, the authors measured epigenetic age acceleration (EAA) during and after cancer treatment and its association with inflammation and fatigue, which is a debilitating symptom in patients with cancer.
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Gut Microbiome Associated with the Psychoneurological Symptom Cluster in Patients with Head and Neck Cancers
Jinbing Bai,Deborah Watkins Bruner,Veronika Fedirko,Jonathan J. Beitler,Chao Zhou,Jianlei Gu,Hongyu Zhao,I-Hsin Lin,Cynthia E Chico,Kristin Higgins,Dong M. Shin,Nabil F. Saba,Andrew H. Miller,Canhua Xiao +13 more
TL;DR: It is suggested that the diversity and abundance of the gut microbiome play a potential role in developing PNS among cancer patients, and glycan metabolism and vitamin metabolism were different between the high and low PNS clusters pre- and post-RT.
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Pilot study of combined aerobic and resistance exercise on fatigue for patients with head and neck cancer: Inflammatory and epigenetic changes
Canhua Xiao,Jonathan J. Beitler,Kristin Higgins,Cynthia E Chico,Janice S. Withycombe,Ying Zhu,Hongyu Zhao,I-Hsin Lin,Fangyong Li,Sangchoon Jeon,Melinda L. Irwin,Deborah Watkins Bruner,Andrew H. Miller,Rebecca A. Gary +13 more
TL;DR: It is suggested that exercise may improve physical performance and reduce fatigue, which could be further linked to decreased inflammation, during active radiotherapy for HNC patients.
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The role of the gut microbiome in cancer-related fatigue: pilot study on epigenetic mechanisms
Canhua Xiao,Veronika Fedirko,Jonathan J. Beitler,Jinbing Bai,Gang Peng,Chao Zhou,Jianlei Gu,Hongyu Zhao,I-Hsin Lin,Cynthia E Chico,Sangchoon Jeon,Tish Knobf,Karen N. Conneely,Kristin Higgins,Dong M. Shin,Nabil F. Saba,Andrew H. Miller,Deborah Watkins Bruner +17 more
TL;DR: Results from functional pathways and DNA methylation analyses indicate that inflammation is likely to be the major driver in the gut-brain axis for cancer-related fatigue.
Association Among Glucocorticoid Receptor Sensitivity, Fatigue, and Inflammation in Patients With Head and Neck Cancer
Canhua Xiao,Ronald C. Eldridge,Jonathan J. Beitler,Kristin Higgins,Cynthia E Chico,Jennifer C. Felger,Evanthia C. Wommack,Tish Knobf,Nabil F. Saba,Dong M. Shin,Deborah Watkins Bruner,Andrew H. Miller +11 more
TL;DR: It is indicated that HNC patients with cancer-related fatigue may exhibit a decreased capacity for glucocorticoids to regulate inflammatory processes, as evidenced by a lower increase in GR sensitivity.