Cuishan Guo
China Medical University (PRC)
9 Papers
Cuishan Guo is an academic researcher from China Medical University (PRC). The author has contributed to research in topics: Endometriosis & Malignant transformation. The author has an hindex of 4, co-authored 8 publications.
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Papers
Identification of Claudin-6 as a Molecular Biomarker in Pan-Cancer Through Multiple Omics Integrative Analysis
TL;DR: Zhang et al. as discussed by the authors explored CLDN6 through multiple omics data integrative analysis, including gene expression level in pan-cancer and comparison of CLDN 6 expression in different molecular subtypes and immune subtypes of pan cancer, targeted protein, biological functions, molecular signatures, diagnostic value, and prognostic value in pan cancer.
Inducing malignant transformation of endometriosis in rats by long-term sustaining hyperestrogenemia and type II diabetes.
TL;DR: The induced malignant endometriosis showed similarities with human disease in the pathological process and histomorphological and molecular biological features and the former may suffer a higher risk of canceration.
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Platelet-to-Lymphocyte Ratio and CA125 Level as a Combined Biomarker for Diagnosing Endometriosis and Predicting Pelvic Adhesion Severity
Cuishan Guo,ChiYuan Zhang +1 more
TL;DR: The combined marker was not only positively correlated with pelvic adhesion but also showed a greater diagnostic value and specificity than CA125 alone, indicating that the combined marker may be a potential inflammatory biomarker playing an important role in the diagnosis and assessment of adhesion in endometriosis.
Effect of LIM kinase 1 overexpression on behaviour of endometriosis-derived stromal cells
TL;DR: LIMK1 is overexpressed in ESCs thereby facilitating malignant-like behaviour, including enhanced migration, invasion, proliferation and angiogenesis, all of which contribute to the occurrence and development of endometriosis.
8
Oestrogen up-regulates DNMT1 and leads to the hypermethylation of RUNX3 in the malignant transformation of ovarian endometriosis
TL;DR: It was demonstrated that hypermethylation of the RUNX3 was related to the malignant transformation of endometriosis and that this process was relatedto corresponding changes in the eutopic endometrium.