Cuihong Wang
Tianjin Urban Construction Institute
11 Papers
34 Citations
Cuihong Wang is an academic researcher from Tianjin Urban Construction Institute. The author has contributed to research in topics: Carbazole & Fluorescence. The author has an hindex of 4, co-authored 11 publications.
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Papers
A benzindole substituted carbazole cyanine dye: a novel targeting fluorescent probe for parallel c-myc G-quadruplexes
Dayong Lin,Xuening Fei,Xuening Fei,Yingchun Gu,Yingchun Gu,Cuihong Wang,Yalin Tang,Li Ran,Jianguo Zhou +8 more
TL;DR: A novel cyanine dye, composed of benzindole and carbazole, is designed and synthesised and it can be said that the dye is an excellent targeting fluorescent probe for c-myc G-quadruplexes.
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A light-up probe targeting for Bcl-2 2345 G-quadruplex DNA with carbazole TO.
Yingchun Gu,Dayong Lin,Yalin Tang,Xuening Fei,Xuening Fei,Cuihong Wang,Baolian Zhang,Jianguo Zhou +7 more
TL;DR: A facile approach with excellent sensitive, good selectivity and quick response for bcl-2 2345 G-quadruplex was developed and may be used for antitumor recognition or antitumors agents.
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Interacted mechanism of functional groups in ligand targeted with folate receptor via docking, molecular dynamic and MM/PBSA.
TL;DR: Twenty novel compounds with different functional groups (-COOH, -OH, -NH2 and -CH3) were designed to study the interaction mechanism of ligands with folate receptors (FRs), providing a theoretical basis for the design of novel compounds targeted with FRs.
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Novel fluorescent antifolates that target folate receptors α and β: Molecular dynamics and density functional theory study.
TL;DR: Nine novel fluorescent antifolates, 1-9, were designed and docked with FRα and FRβ and the hydrogen bond properties of compounds 7, 8 and 9 are promising candidate in distinguishing FRα from FRβ.
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Type and size effect of functional groups on the novel antifolate target recognition folate receptors α and β: Docking, molecular dynamics and MM/PBSA study.
TL;DR: The data show that introducing long functional groups in folate will increase the binding affinity with FRα but will decrease the bindingAffinity with FRβ, which provides a strategy for the design of novel antifolates targeted to FRα.
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