Cristina Colombo
Vita-Salute San Raffaele University
226 Papers
1.9K Citations
Cristina Colombo is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Bipolar disorder & Mood disorders. The author has an hindex of 53, co-authored 211 publications. Previous affiliations of Cristina Colombo include University of Milan & Università telematica San Raffaele.
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Papers
Lithium and GSK-3β promoter gene variants influence cortical gray matter volumes in bipolar disorder
Francesco Benedetti,Sara Poletti,Daniele Radaelli,Clara Locatelli,Adele Pirovano,Cristina Lorenzi,Benedetta Vai,Benedetta Vai,Irene Bollettini,Andrea Falini,Enrico Smeraldi,Cristina Colombo +11 more
TL;DR: The results suggest that the clinical effects of lithium associate with a neurotrophic effect on the whole brain, probably mediated by GSK-3β inhibition.
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White Matter Microstructure in Bipolar Disorder Is Influenced by the Interaction between a Glutamate Transporter EAAT1 Gene Variant and Early Stress.
Sara Poletti,Irene Bollettini,Cristina Lorenzi,Alice Vitali,S. Brioschi,Alessandro Serretti,Cristina Colombo,Francesco Benedetti +7 more
TL;DR: It is hypothesize that after exposure to high levels of ACE G/G homozygotes are more vulnerable to stress reporting the highest damage as a consequence of an excess of free glutamate.
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Influence of postpartum onset on the course of mood disorders
TL;DR: Preliminary findings suggest that PPO mood disorders may be characterized by a less recurrent time course and the role of comorbid personality disorders and treatment should be elucidated.
Recurrence of bipolar mania is associated with catechol-O-methyltransferase Val(108/158)Met polymorphism.
Francesco Benedetti,Sara Dallaspezia,Clara Locatelli,Daniele Radaelli,Sara Poletti,Cristina Lorenzi,Adele Pirovano,Cristina Colombo,Enrico Smeraldi +8 more
TL;DR: It is suggested that rs4680 could be an inheritable aspect of the mechanisms of dopamine regulation that influence the individual susceptibility of patients with bipolar disorder to develop manic episodes of illness.
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Successful antidepressant chronotherapeutics enhance fronto-limbic neural responses and connectivity in bipolar depression.
Benedetta Vai,Benedetta Vai,Sara Poletti,Daniele Radaelli,Sara Dallaspezia,Chiara Bulgarelli,Clara Locatelli,Irene Bollettini,Andrea Falini,Cristina Colombo,Enrico Smeraldi,Francesco Benedetti +11 more
TL;DR: A successful antidepressant treatment was associated with an increased functional activity and connectivity within cortico-limbic networks, suggesting the possible role of these measures in providing possible biomarkers for treatment efficacy.
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