Cris A. Slentz

TL;DR: In this paper, the effects of the amount and intensity of exercise on lipoproteins were investigated in a prospective, randomized study, where a total of 111 sedentary, overweight men and women with mild-to-moderate dyslipidemia were randomly assigned to participate for six months in a control group or for approximately eight months in one of three exercise groups: high-amount-high-intensity exercise, the caloric equivalent of jogging 20 mi (32.0 km) per week at 65 to 80 percent of peak oxygen consumption; low-amount -high-intensive exercise

TL;DR: Findings strongly suggest that, absent changes in diet, a higher amount of activity is necessary for weight maintenance and that the positive caloric imbalance observed in the overweight controls is small and can be reversed by a modest amount of exercise.

TL;DR: Balancing time commitments against health benefits, it appears that AT is the optimal mode of exercise for reducing fat mass and body mass, while a program including RT is needed for increasing lean mass in middle-aged, overweight/obese individuals.

TL;DR: Elevated concentrations of large, neutral amino acids were independently associated with insulin resistance and fatty acids were inversely related to the pancreatic response to glucose, suggesting that these metabolic intermediates might play a role in the progression to type 2 diabetes.