Cosima Thon
Otto-von-Guericke University Magdeburg
21 Papers
14 Citations
Cosima Thon is an academic researcher from Otto-von-Guericke University Magdeburg. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 3, co-authored 8 publications.
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Papers
Fusobacterium nucleatum is associated with worse prognosis in Lauren's diffuse type gastric cancer patients.
Ellen Teresa Boehm,Cosima Thon,Juozas Kupcinskas,Ruta Steponaitiene,Jurgita Skieceviciene,Ali Canbay,Peter Malfertheiner,Alexander Link +7 more
TL;DR: Novel evidence is provided for clinical relevance of F. nucleatum in GC by showing an association between F.ucleatum positivity with worse prognosis of patients with Laurens’s diffuse type gastric cancer.
miR-20b and miR-451a Are Involved in Gastric Carcinogenesis through the PI3K/AKT/mTOR Signaling Pathway: Data from Gastric Cancer Patients, Cell Lines and Ins-Gas Mouse Model
Greta Streleckiene,Ruta Inciuraite,Simonas Juzenas,Violeta Salteniene,Ruta Steponaitiene,Ugne Gyvyte,Gediminas Kiudelis,Marcis Leja,Paulius Ruzgys,Saulius Šatkauskas,Eugenija Kupcinskiene,Sabine Franke,Cosima Thon,Alexander Link,Juozas Kupcinskas,Jurgita Skieceviciene +15 more
TL;DR: It is identified that expression of miR-20b andmiR-451a are deregulated in vitro and in vivo and have a tumor suppressive role in GC through regulation of the PI3K/AKT/mTOR signaling pathway.
Microbial composition of tumorous and adjacent gastric tissue is associated with prognosis of gastric cancer
Konrad Lehr,Darja Nikitina,Ramiro Vilchez-Vargas,Ruta Steponaitiene,Cosima Thon,Jurgita Skieceviciene,Denny Schanze,Martin Zenke,Peter Malfertheiner,Juozas Kupcinskas,A. Link +10 more
TL;DR: In this paper , the authors explored the link between gastric cancer prognosis and the mucosal microbial community in tumorous and adjacent gastric tissue using 16S sequencing (V1-V2 region).
Gut microbial similarity in twins is driven by shared environment and aging
Ramiro Vilchez-Vargas,Jurgita Skieceviciene,Konrad Lehr,Greta Varkalaite,Cosima Thon,Mindaugas Urba,Egidijus Morkunas,Vaidutis Kučinskas,Karolina Bauraitė,Denny Schanze,Martin Zenke,Peter Malfertheiner,Juozas Kupcinskas,A. Link +13 more
TL;DR: In this paper , the authors investigated the microbial composition in several gastrointestinal (GI) compartments to evaluate the impact of genetics, delivery mode, diet, household sharing and aging on microbial similarity in monozygotic and dizygotic twins.
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Differential Expression of Long Noncoding RNA HOTAIR in Intestinal Metaplasia and Gastric Cancer
Vytenis Petkevicius,Cosima Thon,Ruta Steponaitiene,Jurgita Skieceviciene,Dainius Jančiauskas,D Jechorek,Peter Malfertheiner,Juozas Kupcinskas,Alexander Link +8 more
TL;DR: HOTAIR expression was associated with GC and preneoplastic changes of stomach mucosa and was only associated with worse prognosis in Lauren diffuse and not intestinal type of GC.
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