Cornelia Stein
University of Cologne
5 Papers
Cornelia Stein is an academic researcher from University of Cologne. The author has contributed to research in topics: Zebrafish & Biology. The author has an hindex of 5, co-authored 5 publications.
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Papers
Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish
TL;DR: Most of the components known in mammals are also present in fish, with clearly recognizable orthologous relationships, and the main innate immune signaling pathways are conserved in mammals and teleost fish.
The role of gamma interferon in innate immunity in the zebrafish embryo.
TL;DR: The results show that the counterparts of the mammalian viral and bacterial interferon-dependent defence functions are in place in zebrafish embryos, and suggest that zebra fish IFN-γ1 and IFn-γ2 are functionally equivalent to mammalian IFN -γ.
In Vivo Analysis of Ifn-γ1 and Ifn-γ2 Signaling in Zebrafish
Dina Aggad,Cornelia Stein,Dirk Sieger,Martine Mazel,Martine Mazel,Pierre Boudinot,Philippe Herbomel,Philippe Herbomel,Jean-Pierre Levraud,Jean-Pierre Levraud,Georges Lutfalla,Georges Lutfalla,Maria Leptin +12 more
TL;DR: The zebrafish genome contains a large number of genes encoding potential cytokine receptor genes as judged by homology to mammalian receptors, and morpholino-mediated loss-of-function analysis is used to screen candidate receptors and identify the components of their receptor complexes.
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Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.
Daniela Welcker,Cornelia Stein,Natália Martins Feitosa,Natália Martins Feitosa,Joy Armistead,Jin-Li Zhang,Steffen Lütke,André Kleinridders,André Kleinridders,Jens C. Brüning,Jens C. Brüning,Sabine A. Eming,Gerhard Sengle,Anja Niehoff,Anja Niehoff,Wilhelm Bloch,Matthias Hammerschmidt +16 more
TL;DR: Transmission electron microscopy revealed ultrastructural basement membrane (BM) alterations at the DEJ and MTJ of Hmcn1-/-mice, pointing to a thus far unknown role of HMCn1 for BM and connective tissue boundary integrity.
Long-chain Acyl-CoA synthetase 4A regulates Smad activity and dorsoventral patterning in the zebrafish embryo.
Rosa Linda Miyares,Rosa Linda Miyares,Cornelia Stein,Bjoern Renisch,Jennifer L. Anderson,Matthias Hammerschmidt,Steven A. Farber,Steven A. Farber +7 more
TL;DR: It is shown that long-chain acyl-CoA synthetase 4a (Acsl4a), an LC-PUFA activating enzyme, is essential for proper patterning of the zebrafish dorsoventral axis and reveals a critical role for Acsl4a in modulating Bmp-Smad activity.
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