Cornelia S. Seitz
United States Department of Veterans Affairs
2 Papers
2 Citations
Cornelia S. Seitz is an academic researcher from United States Department of Veterans Affairs. The author has contributed to research in topics: Transgene & Cellular differentiation. The author has an hindex of 2, co-authored 2 publications.
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Papers
Patent
Method of regulating epithelial growth
Cornelia S. Seitz,Paul A. Khavari +1 more
- 07 Apr 1998
TL;DR: In this article, methods of treating epithelial hyperproliferative disorders and accelerating wound healing, by modulation of NF-λB activity in the epithelium, are disclosed.
2
Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB
TL;DR: Stratified epithelium contains a mitotically active basal layer of cells that cease proliferating, then migrate outwards and undergo terminal differentiation, and NF-κB activation in this tissue, in contrast to its role in other settings, is important for cellular growth inhibition.