Cornelia Heindl
University of Erlangen-Nuremberg
8 Papers
24 Citations
Cornelia Heindl is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Receptor & Protein subunit. The author has an hindex of 5, co-authored 5 publications.
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Papers
GlyR alpha3: an essential target for spinal PGE2-mediated inflammatory pain sensitization.
Robert J. Harvey,Ulrike B. Depner,Heinz Wässle,Seifollah Ahmadi,Cornelia Heindl,Heiko Reinold,Trevor G. Smart,Kirsten Harvey,Burkhard Schütz,Osama M. Abo-Salem,Andreas Zimmer,Pierrick Poisbeau,Hans Welzl,David P. Wolfer,Heinrich Betz,Hanns Ulrich Zeilhofer,Ulrike Müller +16 more
TL;DR: It is demonstrated that inhibition of a specific glycine receptor subtype (GlyR α3) by PGE2-induced receptor phosphorylation underlies central inflammatory pain sensitization and may provide a previously unrecognized molecular target in pain therapy.
Blockade of TNF-α rapidly inhibits pain responses in the central nervous system
Andreas Hess,Roland Axmann,Juergen Rech,Stefanie Finzel,Cornelia Heindl,Silke Kreitz,M. Sergeeva,Marc Saake,Meritxell Garcia,George Kollias,Rainer H. Straub,Olaf Sporns,Arnd Doerfler,Kay Brune,Georg Schett +14 more
TL;DR: It is demonstrated that within 24 h after neutralization of TNF-α, nociceptive CNS activity in the thalamus and somatosensoric cortex, but also the activation of the limbic system, is blocked.
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Kinetics and functional characterization of the glycine receptor α2 and α3 subunit
TL;DR: The results indicate that the GlyRα2 and theglyRα3 subunits act as important subunits for the modulation of glycine receptor kinetics and function.
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Sugar perception in honeybees
Laura Değirmenci,Fábio Luiz Rogé Ferreira,A. Vukosavljevic,Cornelia Heindl,A. Keller,Dietmar Geiger,Ricarda Scheiner +6 more
TL;DR: In this paper , the contributions of all three honeybee sugar receptors (AmGr1-3), combining CRISPR/Cas9 mediated genetic knock-out, electrophysiology and behaviour, were disentangled.
Refinement and reduction in animal experimentation: options for new imaging techniques.
TL;DR: Non-invasive imaging techniques like (functional) magnetic resonance imaging ((f)MRI), positron emission tomography (PET), and optical imaging (OI) allow for the observation of functional changes within the body of e.g. genetically modified animals without pain, suffering or (premature) termination.
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