Corey D. Acker
University of Connecticut Health Center
28 Papers
149 Citations
Corey D. Acker is an academic researcher from University of Connecticut Health Center. The author has contributed to research in topics: Chemistry & Excitatory postsynaptic potential. The author has an hindex of 11, co-authored 21 publications. Previous affiliations of Corey D. Acker include Boston University & University of Connecticut.
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Papers
Palette of fluorinated voltage-sensitive hemicyanine dyes
Ping Yan,Corey D. Acker,Wen-Liang Zhou,Peter D. Lee,Christian Bollensdorff,Adrian Negrean,Jacopo Lotti,Leonardo Sacconi,Leonardo Sacconi,Srdjan D. Antic,Peter Kohl,Huibert D. Mansvelder,Francesco S. Pavone,Leslie M. Loew +13 more
TL;DR: The sensitivity to voltage and the photostability of the new VSDs are shown in a series of experimental preparations ranging in scale from single dendritic spines to whole heart, affording an extended toolkit for optical recording to match a broad range of experimental requirements.
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Beyond two-cell networks: experimental measurement of neuronal responses to multiple synaptic inputs.
TL;DR: The feasibility of extending phase response curve methods to predict the synchronization properties of stellate cells in the rat entorhinal cortex under broader conditions is explored and it is found that models based on weak coupling account for scaling and Poisson process-driven inputs reasonably accurately.
95
Increasing Ca2+ transients by broadening postsynaptic action potentials enhances timing-dependent synaptic depression
TL;DR: The results suggest that modulation of AP width is a potent way to adjust the rules of synaptic plasticity in the EC and are consistent with an elaboration of the calcium-peak-detector model in which downstream signals from voltage-dependent Ca(2+) channels suppress LTP relative to LTD.
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Quantitative assessment of the distributions of membrane conductances involved in action potential backpropagation along basal dendrites.
Corey D. Acker,Srdjan D. Antic +1 more
TL;DR: The hypothesis that a fraction of basal branches may have different membrane properties compared with sister branches in the same dendritic tree is discussed, and the mechanisms underlying two sets of published data involving high-frequency trains of APs and the local generation of sodium spikelets are explored.
64
Single-Voxel Recording of Voltage Transients in Dendritic Spines
TL;DR: Sensitive recording of membrane potential in single dendritic spines in cortical neurons within a brain slice using two-photon excitation and a new, fluorinated, intracellularly loaded organic dye, di-2-AN(F)EPPTEA is reported.
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