Constanza Lisdero
University of Buenos Aires
12 Papers
81 Citations
Constanza Lisdero is an academic researcher from University of Buenos Aires. The author has contributed to research in topics: Nitric oxide & Peroxynitrite. The author has an hindex of 8, co-authored 12 publications.
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Papers
Nitric oxide regulates oxygen uptake and hydrogen peroxide release by the isolated beating rat heart
Juan José Poderoso,Jorge G. Peralta,Constanza Lisdero,Maria Cecilia Carreras,Marcelo Radisic,Francisco J. Schopfer,Enrique Cadenas,Alberto Boveris +7 more
TL;DR: In the intact heart, finely adjusted NO concentrations regulate mitochondrial O2uptake and superoxide anion production (reflected by H2O2), which in turn contributes to the physiological clearance of NO through peroxynitrite formation.
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Peroxynitrite-mediated mitochondrial dysfunction.
Jorge Boczkowski,Constanza Lisdero,Sophie Lanone,Maria Cecilia Carreras,Michel Aubier,Juan José Poderoso +5 more
TL;DR: Experimental evidence showed that exogenous and endogenous peroxynitrite causes alterations of the structure and function of mitochondrial proteins, leading to mitochondrial dysfunction and cellular or organ injury.
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Decreased pulmonary and tracheal smooth muscle expression and activity of type 1 nitric oxide synthase (nNOS) after ovalbumin immunization and multiple aerosol challenge in guinea pigs.
Abdoulaye Samb,Marina Pretolani,Anh Tuan Dinh-Xuan,Hakima Ouksel,Jacques Callebert,Constanza Lisdero,Michel Aubier,Jorge Boczkowski +7 more
TL;DR: It is concluded that OVA stimulation in immunized guinea pigs induced a transient reduction in NOS1 protein expression and activity in the respiratory system, which probably participates in airway hyperresponsiveness.
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The Mitochondrial Interplay of Ubiquinol and Nitric Oxide in Endotoxemia
Constanza Lisdero,Maria Cecilia Carreras,Alain Meulemans,Mariana Melani,Michel Aubier,Jorge Boczkowski,Juan José Poderoso +6 more
TL;DR: The chapter provides the methodological bases that support the relation between UQ content, mitochondrial NO steady-state concentration, and peroxynitrite-mediated mitochondrial damage in representative organs and elaborates the ubiquinone content and NO-induced hydrogen peroxide production by mitochondria.
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