Congxin Li
German Cancer Research Center
13 Papers
Congxin Li is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 3 publications.
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Papers
Frequency Modulation of Transcriptional Bursting Enables Sensitive and Rapid Gene Regulation.
TL;DR: It is shown that quantitating the temporal regulation of key gene states (transcriptionally inactive, active, and refractory) provides a parsimonious framework for analyzing gene regulation and demonstrates the relevance of a kinetic, non-equilibrium framework for understanding transcriptional regulation.
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Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis
Mina Morcos,Congxin Li,Clara M. Munz,A. Greco,N. Dressel,Susanne Reinhardt,Katrin Sameith,Andreas Dahl,Nils B. Becker,Axel Roers,Thomas Höfer,Alexander Gerbaulet +11 more
TL;DR: In this paper , the authors chart native lineage pathways emanating from HSCs and define their physiological regulation by computationally integrating experimental approaches for fate mapping, mitotic tracking, and single-cell RNA sequencing.
Tu1271: T-BOX TRANSCRIPTION FACTOR 19 PROMOTES HEPATOCELLULAR CARCINOMA METASTASIS THROUGH UPREGULATING EGFR AND RAC1
Xiaoyu Ji,Xiaoping Chen,Bixiang Zhang,Meng Xie,Tongyue Zhang,Xiang-Yuan Luo,Danfei Liu,Yangyang Feng,Yijun Wang,Mengyu Sun,Congxin Li,Wen-Jin Huang,Limin Xia +12 more
TL;DR: The role of TBX19 in HCC metastasis is explored, which is one of the most upregulated TBX family genes in human HCC tissues and Targeting this signaling pathway may offer a potential therapeutic strategy to efficiently restrainTBX19-mediated HCC melanoma metastasis.
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Position-dependent effects of RNA-binding proteins in the context of co-transcriptional splicing
TL;DR: In this paper , the authors derived mathematical models describing how splicing decisions in a three-exon gene are made by combinatorial spliceosome binding to splice sites during ongoing transcription.
Toll-like receptor 4-mediated endoplasmic reticulum stress induces intestinal paneth cell damage in mice following CLP-induced sepsis
TL;DR: In this paper , the role of TLR4 in intestinal Paneth cell damage by histological, polymerase chain reaction, western-blot analyses was investigated in various organs of septic mice.