Congran Li
Peking Union Medical College
53 Papers
170 Citations
Congran Li is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Biology & Chemistry. The author has an hindex of 13, co-authored 41 publications. Previous affiliations of Congran Li include Georgia State University.
Chat about Author
Papers
Arginine racemization by coupled catabolic and anabolic dehydrogenases
Congran Li,Chung-Dar Lu +1 more
TL;DR: It is proposed that DauA and DauB are coupled catabolic and anabolic dehydrogenases to perform d-to-l racemization of arginine, which serves as prerequisite of d-arginine utilization through l-argInine catabolic pathways.
77
The multifaceted proteins MvaT and MvaU, members of the H-NS family, control arginine metabolism, pyocyanin synthesis, and prophage activation in Pseudomonas aeruginosa PAO1.
TL;DR: The mvaT mvaU double mutant was viable, and depletion of MvaT and MvaU had serious effects on a variety of physiological functions in P. aeruginosa.
54
Genetic basis of high level aminoglycoside resistance in Acinetobacter baumannii from Beijing, China
Lu Nie,Yuemeng Lv,Min Yuan,Xinxin Hu,Tongying Nie,Xinyi Yang,Guoqing Li,Jing Pang,Jingpu Zhang,Congran Li,Xiukun Wang,Xuefu You +11 more
TL;DR: The objective of this study was to investigate the genetic basis of high level aminoglycoside resistance in Acinetobacter baumannii clinical isolates from Beijing, China and found that armA was reported to be able to cause high levelAminogly coside resistance to most of the clinical important aminglycosides (gentamicin, amikacin, tobramycin, etc).
52
Regulation and Characterization of the dadRAX Locus for d-Amino Acid Catabolism in Pseudomonas aeruginosa PAO1
TL;DR: The results from this study clearly demonstrate DadA to be the enzyme solely responsible for the proposed D-amino acid dehydrogenase activity of broad substrate specificity and the physiological functions of DadRAX in catabolism of several D-Amino acids and support L-Ala as the signal molecule for induction of the dadAX genes through DadR binding to several putative operator sites.
51
In vivo antibacterial activity of nemonoxacin, a novel non-fluorinated quinolone
Congran Li,Yi Li,Guoqing Li,Xinyi Yang,Wei-Xin Zhang,Ren-Hui Lou,Jing-Fang Liu,Min Yuan,Philip Huang,Shan Cen,Li-Yan Yu,Li-Xun Zhao,Jian-Dong Jiang,Xuefu You +13 more
TL;DR: The results validated the potent efficacy of nemonoxacin in vivo and warrants investigation of its clinical use.
42