Cong Xu
Wenzhou Medical College
15 Papers
2 Citations
Cong Xu is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Medicine & Pyroptosis. The author has an hindex of 6, co-authored 9 publications.
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Papers
Role of Pyroptosis in Traumatic Brain and Spinal Cord Injuries.
Xinli Hu,Huanwen Chen,Hui Xu,Yaosen Wu,Chenyu Wu,Chang Jia,Yao Li,Sunren Sheng,Cong Xu,Huazi Xu,Wen-Fei Ni,Kailiang Zhou +11 more
TL;DR: Current knowledge on how pyroptosis is involved in CNS injuries is discussed, focusing on new discoveries regarding how pyproptosis activation occurs, differences between CNS cell types following injury, time-course of inflammatory responses, and key regulatory steps of pyroPTosis.
Carbon monoxide releasing molecule-3 alleviates neuron death after spinal cord injury via inflammasome regulation.
Gang Zheng,Yu Zhan,Haoli Wang,Zucheng Luo,Fanghong Zheng,Yifei Zhou,Yaosen Wu,Sheng Wang,Yan Wu,Guangheng Xiang,Cong Xu,Huazi Xu,Naifeng Tian,Xiaolei Zhang +13 more
TL;DR: CO may alleviate neuron death and improve motor functional recovery in SCI through IRE1 regulation, and administration of CO could be a promising therapeutic strategy for SCI.
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MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis
Haiwei Ma,Cheng-long Xie,Zhengtai Chen,Gaolu He,Zihan Dai,Hancheng Cai,Haojie Zhang,Hongwei Lu,Hongqiang Wu,Xinli Hu,Kailiang Zhou,Gang Zheng,Huazi Xu,Cong Xu +13 more
TL;DR: In this paper , the expression changes of MFG-E8 in the intervertebral disc degeneration (IVDD) process were investigated and the role and mechanism of E8 was explored.
Bone-targeting delivery of platelet lysate exosomes ameliorates glucocorticoid-induced osteoporosis by enhancing bone-vessel coupling
Gang Zheng,Haiwei Ma,Guang-Heng Xiang,Gaolu He,Hancheng Cai,Zihan Dai,Yan-Lin Chen,Yan Lin,Huazi Xu,Wen-Fei Ni,Cong Xu,Haixiao Liu,Xiang-Yang Wang +12 more
TL;DR: In this article , platelet exosomes (PL-exo) were isolated to enrich the platelet-derived GFs, followed by conjugating with alendronate (ALN) grafted PEGylated phospholipid (DSPE-PEG-ALN).
CO-Releasing Molecule (CORM)-3 Ameliorates Spinal Cord-Blood Barrier Disruption Following Injury to the Spinal Cord
Gang Zheng,Fanghong Zheng,Zucheng Luo,Haiwei Ma,Dongdong Zheng,Guang-Heng Xiang,Cong Xu,Yifei Zhou,Yaosen Wu,Naifeng Tian,Yan Wu,Tan Zhang,Wen-Fei Ni,Sheng Wang,Huazi Xu,Xiaolei Zhang +15 more
TL;DR: It is demonstrated that the exogenous increasing of CO by CORM-3 blocked the tight junction (TJ) protein degeneration and neutrophils infiltration, subsequently suppressed the BSCB damage and improved the motor recovery after SCI.