6 Papers
11 Citations
Cong Xi is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Apoptosis & Sepsis. The author has an hindex of 5, co-authored 5 publications.
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Papers
Melatonin attenuates sepsis-induced cardiac dysfunction via a PI3K/Akt-dependent mechanism.
TL;DR: It is demonstrated that melatonin mitigates myocardial injury in sepsis via PI3K/Akt signaling activation.
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Overexpression of Rcan1-1L Inhibits Hypoxia-Induced Cell Apoptosis through Induction of Mitophagy
TL;DR: Evidence is provided that R can1-1L overexpression induces mitophagy, which in turn contributes to cell survival under hypoxic conditions, revealing for the first time that Rcan1- 1L-induced mitophagic may be used for cardioprotection.
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Resveratrol alleviates sepsis‑induced myocardial injury in rats by suppressing neutrophil accumulation, the induction of TNF‑α and myocardial apoptosis via activation of Sirt1.
TL;DR: Resveratrol has been demonstrated to attenuate myocardial injury in sepsis by decreasing neutrophil accumulation, TNF‑α expression, and myocardian apoptosis via activation of Sirt1 signaling, suggesting a novel therapeutic strategy for the clinical treatment of septicaemia.
Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial.
Jiang-Hong Wang,Jing Zhao,Cong Yan,Cong Xi,Chenglin Wu,Jinbing Zhao,Fengwei Li,Yanhuai R. Ding,Rui Zhang,Shankang Qi,Xingjun Li,Chao Liu,Wanting Hou,Hong Chen,Yiping Wang,Dalei Wu,Kaixian Chen,Hualiang Jiang,He Huang,Hong Ying Liu +19 more
TL;DR: The discovery of DC371739, an indole-containing tetrahydroisoquinoline compound with promising lipid-lowering effects, and its combination with atorvastatin treatment to additively improve dyslipidemia, while providing a potential alternative therapeutic strategy for individuals with statin intolerance.
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Intramyocardial Injection of Recombinant Adeno-Associated Viral Vector Coexpressing PR39/Adrenomedullin Enhances Angiogenesis and Reduces Apoptosis in a Rat Myocardial Infarction Model
TL;DR: It is demonstrated that rAAV-PR39-ADM mitigates myocardial injury by promoting angiogenesis and reducing apoptosis and a potential novel gene therapy-based method that could be used clinically forMyocardial infarction is suggested.