Cong Meng
Texas A&M University
5 Papers
36 Citations
Cong Meng is an academic researcher from Texas A&M University. The author has contributed to research in topics: Leukemia & Gene. The author has an hindex of 3, co-authored 4 publications.
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Papers
Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation
Fen Li,Xuan Yu,Claudia K. Szynkarski,Cong Meng,Beiyan Zhou,Rola Barhoumi,Richard E. White,Cristine L. Heaps,John N. Stallone,Guichun Han +9 more
TL;DR: GPER activation inhibits CASMC proliferation by suppressing cell cycle progression via inhibition of ERK1/2 and Akt phosphorylation, suggesting that GPER may constitute a novel mechanism to suppress intimal migration and/or synthetic phenotype of VSMC.
MiR-150 blocks MLL-AF9-associated leukemia through oncogene repression
Marina Bousquet,Guoqing Zhuang,Cong Meng,Wei Ying,Patali S. Cheruku,Andrew T. Shie,Stephanie W. Wang,Guangtao Ge,Piu Wong,Gang Wang,Stephen Safe,Beiyan Zhou +11 more
TL;DR: It is demonstrated that miR-150 is a potent leukemic tumor suppressor that regulates multiple oncogenes and establishes new, key players for the development of therapeutic strategies to treat MLL-AF9–related leukemia.
37
NR4A Orphan Receptors as Drug Targets
Stephen Safe,Stephen Safe,Syng Ook Lee,Cong Meng,Beiyan Zhou +4 more
- 01 Jan 2015
TL;DR: The in vitro characterization of NR4Al as pro-oncogenic in leukemia cells is in contrast to the tumor suppressor-like activity ofNR4Al in transgenic mouse models, and these differences are currently being investigated.
2
A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation.
Guoqing Zhuang,Cong Meng,Xin Guo,Patali S. Cheruku,Lei Shi,Hang Xu,Honggui Li,Gang Wang,Ashley R. Evans,Stephen Safe,Chaodong Wu,Beiyan Zhou +11 more
TL;DR: In this paper, the authors examined the activity of microRNA-223 (miR-223) and its role in controlling macrophage functions in adipose tissue inflammation and systemic insulin resistance.
Current progress and future perspectives of neoadjuvant anti-PD-1/PD-L1 therapy for colorectal cancer
Zhengyang Yang,Guocong Wu,Xiao Zhang,Jiale Gao,Cong Meng,Yi-Shan Liu,Q. Wei,Liting Sun,Pengyu Wei,Zhigang Bai,Hongwei Yan,Zhongtao Zhang +11 more
TL;DR: Neoadjuvant therapy, mainly including chemotherapy and radiotherapy, not only can reduce clinical stage but also benefit from local control, which can improve clinical symptoms and the quality of life.