Collin Tran
University of Sydney
7 Papers
Collin Tran is an academic researcher from University of Sydney. The author has contributed to research in topics: Sphingosine & Ceramide. The author has an hindex of 4, co-authored 5 publications. Previous affiliations of Collin Tran include University of New South Wales.
Chat about Author
Papers
Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration.
Timothy A. Couttas,Timothy A. Couttas,Nupur Kain,Collin Tran,Collin Tran,Zac Chatterton,John B.J. Kwok,Anthony S. Don,Anthony S. Don +8 more
TL;DR: Gender-specific differences in sphingolipid metabolism in the aging human brain are established, and increasing ceramide and decreasing S1P levels may contribute significantly to a pro-neurodegenerative phenotype in the Aging brain.
60
Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein
Xin Tracy Liu,Long H. Chung,Da Liu,Jinbiao Chen,Yu Huang,Jonathan D. Teo,Xingxing Daisy Han,Yinan Zhao,Fiona H. X. Guan,Collin Tran,Jun Yup Lee,Timothy A. Couttas,Ken Liu,Geoffrey W. McCaughan,Mark D. Gorrell,Anthony S. Don,Shubiao Zhang,Yan-yan Qi +17 more
TL;DR: In this paper , a key sphingolipid metabolic enzyme, sphingosine kinase 2 (SphK2), plays a critical role in NAFLD-associated HCC.
Altered lipid metabolic homeostasis in the pathogenesis of Alzheimer’s disease
Oana C. Marian,Collin Tran,Anthony S. Don +2 more
- 01 Jan 2020
TL;DR: The current knowledge on altered lipid metabolism in AD is described, and how this relates to genetic risk, myelin deterioration, impaired endosomal–lysosomal flux, and the neuropathological hallmarks of the disease are described.
5
Effects of pre-eclampsia on HDL-mediated cholesterol efflux capacity after pregnancy
TL;DR: In this article , the HDL-mediated cholesterol efflux capacity (CEC) is decreased during pregnancy in women with preeclampsia (PE) and whether this persists postpartum is unknown.
2
Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice.
Ryan S. Tonkin,Callum Bowles,Chamini J. Perera,Brooke A Keating,Preet G.S. Makker,Samuel S. Duffy,Justin G. Lees,Collin Tran,Anthony S. Don,Thomas Fath,Lu Liu,Simon J. O'Carroll,Louise F.B. Nicholson,Colin R. Green,Catherine A. Gorrie,Gila Moalem-Taylor +15 more
TL;DR: It is demonstrated that blocking Cx43 hemichannels with Peptide5 after nerve injury attenuates mechanical pain hypersensitivity by specifically targeting the NLRP3 inflammasome in the spinal cord.