100 Papers
426 Citations
Colin Scott is an academic researcher from Commonwealth Scientific and Industrial Research Organisation. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 28, co-authored 89 publications. Previous affiliations of Colin Scott include University of Sheffield.
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Papers
NO sensing by FNR: regulation of the Escherichia coli NO‐detoxifying flavohaemoglobin, Hmp
Hugo Cruz-Ramos,Jason C. Crack,Guanghui Wu,Martin N. Hughes,Colin Scott,Andrew J. Thomson,Jeffrey Green,Robert K. Poole +7 more
TL;DR: FNR can respond to not only O2, but also NO, with major implications for global gene regulation in bacteria, and an NO‐mediated mechanism of hmp regulation by which E.coli responds to NO challenge is proposed.
The enzymatic basis for pesticide bioremediation
Colin Scott,Gunjan Pandey,Carol J. Hartley,Colin J. Jackson,Matthew J. Cheesman,Matthew C. Taylor,Rinku Pandey,Jeevan L. Khurana,Mark G. Teese,Christopher W. Coppin,Khali Weir,Rakesh K. Jain,Rup Lal,Robyn J. Russell,John G. Oakeshott +14 more
TL;DR: This review describes examples of enzymes possessing the major activities employed in the bioremediation of pesticide residues, and some of the strategies by which they are employed.
Identification and characterization of two families of F420H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation
Matthew C. Taylor,Colin J. Jackson,David B. Tattersall,Nigel P. French,Thomas S. Peat,Janet Newman,Lyndall J. Briggs,Gauri V. Lapalikar,Peter M. Campbell,Colin Scott,Robyn J. Russell,John G. Oakeshott +11 more
TL;DR: Nine Mycobacterium smegmatis enzymes that utilize the deazaflavin cofactor F420H2 to catalyse the reduction of the α,β‐unsaturated ester moiety of aflatoxins are identified and a general role for these enzymes in xenobiotic metabolism is discussed.
Physiology, Biochemistry, and Applications of F420- and Fo-Dependent Redox Reactions
Chris Greening,F. Hafna Ahmed,A. Elaaf Mohamed,Brendon M. Lee,Gunjan Pandey,Andrew C. Warden,Colin Scott,John G. Oakeshott,Matthew C. Taylor,Colin J. Jackson +9 more
TL;DR: 5-Deazaflavin cofactors enhance the metabolic flexibility of microorganisms by catalyzing a wide range of challenging enzymatic redox reactions, and the physiological roles of F420 in microorganisms and the biochemistry of the various oxidoreductases that mediate these roles are discussed.
Evolution of atrazine-degrading capabilities in the environment
TL;DR: This review focuses on the enzymes involved in atrazine mineralization and their evolutionary histories, the genetic composition of microbial populations involved inAtrazine degradation and the biotechnologies that have been developed, based on these systems, for the bioremediation of atrazin contamination in the environment.
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