Colin G. Steward
University of Bristol
127 Papers
1.5K Citations
Colin G. Steward is an academic researcher from University of Bristol. The author has contributed to research in topics: Transplantation & Barth syndrome. The author has an hindex of 45, co-authored 127 publications. Previous affiliations of Colin G. Steward include St. Michael's GAA, Sligo & Bristol Royal Hospital for Children.
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Papers
Erratum to: Barth syndrome without tetralinoleoyl cardiolipin deficiency: a possible ameliorated phenotype
Ann Bowron,Julie Honeychurch,Maggie Williams,Beverley Tsai-Goodman,Nicol Clayton,Lucy Jones,Graham J. Shortland,Shakeel A. Qureshi,Simon Heales,Colin G. Steward +9 more
TL;DR: This work presents a meta-analysis of seven functional classes of Barth syndrome mutation and its role in infectious disease and suggests that these classes are related to infectious disease-related cancers.
Long-term outcomes of hematopoietic stem cell transplantation for severe treatment-resistant autoimmune cytopenia in children
Marco Rabusin,John A. Snowden,Paul Veys,Pierre Quartier,Jean Hughes Dalle,Catharina Dhooge,Paolo Bartolomeo,Maria Gonzalez-Vicent,Brenda Gibson,Arturo Iriondo,Herbert Juergens,Igor Lisukov,Chiara Messina,Valérie Mialou,Colin G. Steward,Christian Urban,Marleen Renard,Nagua Giurici,Christina Peters,Manuela Badoglio,Luca Ronfani,Giorgio Dini,Dominique Farge,Riccardo Saccardi +23 more
TL;DR: Based on the limited numbers of subjects in this retrospective analysis, both allogeneic and autologous HSCT may induce complete and persistent responses in approximately one-half of pediatric patients with severe refractory autoimmune cytopenia, although treatment-related toxicity is high.
Cardiolipin fingerprinting of leukocytes by MALDI-TOF/MS as a screening tool for Barth syndrome
Roberto Angelini,Simona Lobasso,Ruggiero Gorgoglione,Ann Bowron,Colin G. Steward,Angela Corcelli +5 more
TL;DR: The method of lipid analysis described represents an important additional tool for the diagnosis of BTHS and potentially enables therapeutic monitoring of drug targets, which have been shown to ameliorate abnormal CL profiles in cells.
Neurological aspects of osteopetrosis
TL;DR: The least understood form of the osteopetroses is neuronopathic OP [OP and infantile neuroaxonal dystrophy, MIM (Mendelian inheritance in man) 600329] which causes rapid neurodegeneration and death within the first year.
Minimal Residual Disease Status Before Allogeneic Bone Marrow Transplantation Is an Important Determinant of Successful Outcome for Children and Adolescents With Acute Lymphoblastic Leukemia
C. J. C. Knechtli,Nicholas Goulden,Jeremy Hancock,Victoria Grandage,Emma L. Harris,R. J. Garland,Claire Jones,A. W. Rowbottom,Linda P. Hunt,Ann Green,Emer Clarke,Alan Lankester,Jacqueline M. Cornish,Derwood Pamphilon,Colin G. Steward,Anthony Oakhill +15 more
TL;DR: Results suggest that MRD analysis could be used routinely in this setting to allow identification of patients with resistant leukemia and of those with more responsive disease (who may be candidates for randomized trials of BMT versus modern intensive relapse chemotherapy).