3 Papers
Colette Dib is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Population & Candidate gene. The author has an hindex of 3, co-authored 3 publications.
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Papers
Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level
Olivier Harismendy,Vikas Bansal,Gaurav Bhatia,Masakazu Nakano,Mike Scott,Xiaoyun Wang,Colette Dib,Edouard Turlotte,Jack C. Sipe,Sarah S. Murray,Jean-François Deleuze,Vineet Bafna,Eric J. Topol,Eric J. Topol,Kelly A. Frazer +14 more
TL;DR: This study, which is one of the first reports of a sequence-based association study using next-generation sequencing of candidate genes, provides insights into study design and analysis approaches and demonstrates the importance of examining regulatory elements rather than exclusively focusing on exon sequences.
No replication of genetic association between candidate polymorphisms and Alzheimer's disease.
Emmanuelle Cousin,Sandrine Mace,Corinne Rocher,Colette Dib,Gaëlle Muzard,Didier Hannequin,Laurent Pradier,Jean-François Deleuze,Emmanuelle Génin,Alexis Brice,Dominique Campion +10 more
TL;DR: Despite a careful replication study design, this study failed to validate the initial findings for any of these variants, with the possible exception of MAPT, SORL1 and TFCP2 for which some nominal but inconsistent evidence of association was observed.
Genome-scan for bipolar disorder with sib-pair families in the Sardinian population: a new susceptibility locus on chromosome 1p22-p21?
Maria Del Zompo,Giovanni Severino,Raffaella Ardau,Caterina Chillotti,Mariapaola Piccardi,Colette Dib,Gaëlle Muzard,Stéphane Soubigou,Murielle Derock,Raphaël Fournel,Yves Vaubien,Sandrine Roche,Laurent Bowen-Squires,Emmanuelle Génin,Emmanuelle Cousin,Jean-Francois Deleuze,Nicole Faucon Biguet,Jacques Mallet,Rolando Meloni +18 more
TL;DR: This study suggests that the 1p22–p21 region may contain a new locus participating to the genetic susceptibility to bipolar disorder and reproduces positive linkage for several other loci already implicated in this pathology.