Coby Out-Luiting
Leiden University Medical Center
16 Papers
198 Citations
Coby Out-Luiting is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: In vivo & Medicine. The author has an hindex of 14, co-authored 15 publications. Previous affiliations of Coby Out-Luiting include Leiden University.
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Papers
High-risk Melanoma Susceptibility Genes and Pancreatic Cancer, Neural System Tumors, and Uveal Melanoma across GenoMEL
Alisa M. Goldstein,May Chan,Mark Harland,Elizabeth M. Gillanders,Nicholas K. Hayward,Marie-Françoise Avril,Esther Azizi,Giovanna Bianchi-Scarrà,D. Timothy Bishop,Brigitte Bressac-de Paillerets,William Bruno,Donato Calista,Lisa A. Cannon Albright,Florence Demenais,David E. Elder,Paola Ghiorzo,Nelleke A. Gruis,Johan Hansson,David W. Hogg,Elizabeth A. Holland,Peter A. Kanetsky,Richard F. Kefford,Maria Teresa Landi,Julie Lang,Sancy A. Leachman,Rona M. MacKie,Veronica Magnusson,Graham J. Mann,Kristin B. Niendorf,Julia A. Newton Bishop,Jane M. Palmer,Susana Puig,Joan Anton Puig-Butille,Femke A. de Snoo,Mitchell S. Stark,Hensin Tsao,Margaret A. Tucker,Linda Whitaker,Emanuel Yakobson,Joseph Malvehy,Celia Badenas,R. Cervera,Francisco Cuellar,Francisco Cuellar,Rosa M. Martí,Joan Brunet-Vidal,Guang Yang,Nicholas G. Martin,David C. Whiteman,Adèle C. Green,Joanne F. Aitken,Paola Minghetti,Michela Mantelli,Lorenza Pastorino,Sabina Nasti,Sara Gargiulo,Sara Gliori,Sushila Mistry,Juliette Randerson-Moor,Wilma Bergman,Jeanet A.C. ter Huurne,Clasine van der Drift,Leny van Mourik,Coby Out-Luiting,Frans A. van Nieuwpoort,Valérie Chaudru,Agnès Chompret,Caroline Kanengiesser,J. L. Michel,Florent Grange,B. Sassolas,Jean -Marc Limacher,D. Couillet,F. Truchetet,J. P. Cesarini,F. Boitier,Jacqueline Chevrant-Breton,Christine Lasset,Michel Longy,Pascal Joly,Nicole Basset-Seguin,T. Lesimple,Catherine Dugast,Arupa Ganguly,Michael Ming,Patricia Van Belle,Anton Platz,Suzanne Egyhazi,Rainer Tuominen,Diana Linden,Helen Schmid,Alon Scope,Felix Pavlotsky,Eitan Friedman,Mark J. Eliason,Christian Ingvar,Åke Borg,Johan Westerdahl,Anna Måsbäck,Håkan Olsson +99 more
TL;DR: This GenoMEL study provides the most extensive characterization of mutations in high-risk melanoma susceptibility genes in families with three or more melanoma patients yet available and there was little evidence for an association between CDKN2A mutations and NST, but there was a marginally significant association between NST and ARF.
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Epigenetic inactivation of RASSF1a in uveal melanoma.
Willem Maat,Pieter A. van der Velden,Coby Out-Luiting,Maria Plug,Anita Dirks-Mulder,Martine J. Jager,Nelleke A. Gruis +6 more
TL;DR: Evaluated data show that RASSF1a methylation is a common epigenetic event in uveal melanoma development, potentially of clinical relevance and might serve as a tumor marker and as a possible target for therapeutic intervention.
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THE ACTION SPECTRA FOR UV‐INDUCED SUPPRESSION OF MLR and MECLR SHOW THAT IMMUNOSUPPRESSION IS MEDIATED BY DNA DAMAGE
TL;DR: To obtain a better understanding of the mechanism by which UVB radiation decreases the alloactivating capacity of in vitro‐irradiated cells, action spectra for the mixed lymphocyte reaction and MECLR were determined, suggesting that they share a common mechanism for UV‐induced suppression.
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Analysis of the protective effect of topical sunscreens on the UVB-radiation -induced suppression of the mixed-lymphocyte reaction
A. Mieke Mommaas,Marinus G C van Praag,Jan Nico Bouwes Bavinck,Coby Out-Luiting,Bert J. Vermeer,Frans H.J. Claas +5 more
TL;DR: The mixed-lymphocyte reaction was used to test the protective capacity of several sunscreens against UVB-radiation-induced suppression of the immune response, and results suggest that the MED is not an accurate method to determine protection against UV-induced immunologic damage.
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Broad-Spectrum Sunscreens Offer Protection Against Urocanic Acid Photoisomerization by Artificial Ultraviolet Radiation in Human Skin1
Renate G. van der Molen,Coby Out-Luiting,Hansjürgen Driller,Frans H.J. Claas,Henk K. Koerten,A. Mieke Mommaas +5 more
TL;DR: UCA isomerization is an excellent method to determine sunscreen efficacy and that broad-spectrum sunscreens offer good immunoprotection.
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