Clifford J. Rosen
Maine Medical Center
717 Papers
6.3K Citations
Clifford J. Rosen is an academic researcher from Maine Medical Center. The author has contributed to research in topics: Osteoporosis & Bone density. The author has an hindex of 111, co-authored 655 publications. Previous affiliations of Clifford J. Rosen include Veterans Health Administration & Thomas Jefferson University.
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Papers
Differentiating between orchiectomized rats and controls using measurements of trabecular bone density : a comparison among dxa, histomorphometry, and peripheral quantitative computerized tomography
Harold N. Rosen,S. Tollin,R. Balena,V. L. Middlebrooks,Wesley G. Beamer,L. R. Donohue,Clifford J. Rosen,Adrian K. Turner,Michael F. Holick,Susan L. Greenspan +9 more
TL;DR: PQCT may be a reasonable surrogate for measurements by histomorphometry in studies of rat bone metabolism, and all three methods can demonstrate the effect of orchiectomy on trabecular bone.
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Isolation, Culture, and Differentiation of Bone Marrow Stromal Cells and Osteoclast Progenitors from Mice
TL;DR: One method that yields a mixed population of BMSCs and HSCs and one method that attempts to separate the two cell populations based on adherence, which provide cells suitable for osteogenic and adipogenic differentiation experiments as well as functional assays are presented.
Low bone mineral density in adults with previous hypothalamic-pituitary tumors: correlations with serum growth hormone responses to GH-releasing hormone, insulin-like growth factor I, and IGF binding protein 3.
TL;DR: It is indicated that adults with previous HPTs have significantly lower spine and hip BMD compared with healthy controls, regardless of gonadal steroid therapy, and that this premature bone loss is associated with relative GHD.
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Cortical tibial bone volume in two strains of mice: effects of sciatic neurectomy and genetic regulation of bone response to mechanical loading.
Y Kodama,H.P Dimai,Jon E. Wergedal,Matilda H.-C. Sheng,R. Malpe,S. Kutilek,Wesley G. Beamer,L.R. Donahue,Clifford J. Rosen,David J. Baylink,John R. Farley +10 more
TL;DR: Findings indicate that B6 mice are more sensitive to endosteal bone loss from hindlimb immobilization than C3H mice, and mechanical loading/unloading as a possible determinant of the bone density difference between these inbred strains of mice is indicated.
99
Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: A randomized trial
Catherine M. Gordon,Estherann Grace,S. Jean Emans,Henry A. Feldman,Elizabeth Goodman,Kelly A. Becker,Clifford J. Rosen,Caren M. Gundberg,Meryl S. LeBoff +8 more
TL;DR: Replicating results from studies of the elderly, DHEA resulted in improvements in specific psychological parameters in these young women with anorexia nervosa, evidenced by the positive correlation between increases in hip DXA measurements and IGF-I and significant increases in bone formation markers.
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