Clement Pillainayagam
Rush University Medical Center
7 Papers
25 Citations
Clement Pillainayagam is an academic researcher from Rush University Medical Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 3 publications. Previous affiliations of Clement Pillainayagam include University of Texas MD Anderson Cancer Center.
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Papers
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.
Linda M. Liau,Keyoumars Ashkan,David Tran,Jian Campian,John E. Trusheim,Charles S. Cobbs,Jason Heth,Michael Salacz,Sarah A. Taylor,Stacy D. D’Andre,Fabio M. Iwamoto,Edward J. Dropcho,Yaron A. Moshel,Kevin A. Walter,Clement Pillainayagam,Robert Aiken,Rekha Chaudhary,Samuel Goldlust,Daniela A. Bota,Paul Duic,Jai Grewal,Heinrich Elinzano,Steven A. Toms,Kevin O. Lillehei,Tom Mikkelsen,Tobias Walbert,Steven R. Abram,Andrew Brenner,Steven Brem,Matthew G. Ewend,Simon Khagi,Jana Portnow,Lyndon Kim,William G. Loudon,Reid C. Thompson,David Avigan,Karen Fink,Francois J. Geoffroy,Scott Lindhorst,Jose Lutzky,Andrew E. Sloan,Gabriele Schackert,Dietmar Krex,Hans-Jorg Meisel,Julian Wu,Raphael P. Davis,Christopher Duma,Arnold B. Etame,David Mathieu,Santosh Kesari,David Piccioni,Manfred Westphal,David S. Baskin,Pamela Z. New,Michel Lacroix,Sven-Axel May,Timothy J. Pluard,Victor Tse,Richard M. Green,John L. Villano,Michael Pearlman,Kevin Petrecca,Michael Schulder,Lynne Taylor,Anthony E. Maida,Robert M. Prins,Timothy F. Cloughesy,Paul Mulholland,Marnix L. Bosch +68 more
TL;DR: Addition of DCVax-L to standard therapy is feasible and safe in glioblastoma patients, and may extend survival, and overall adverse events withDCVax were comparable to standard Therapy alone.
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma
Linda M. Liau,Keyoumars Ashkan,Steven Brem,Jian Campian,John E. Trusheim,Fabio M. Iwamoto,David Tran,George Ansstas,Charles Cobbs,Jason Heth,Michael Salacz,Stacy D. D’Andre,Robert Aiken,Yaron A. Moshel,Joo Yeon Nam,Clement Pillainayagam,Stephanie Ann Wagner,Kevin A. Walter,Rekha Chaudhary,Samuel Goldlust,Ian Lee,Daniela A. Bota,Heinrich Elinzano,Jai Grewal,Kevin O. Lillehei,Tom Mikkelsen,Tobias Walbert,Steven R. Abram,Andrew Brenner,Matthew G. Ewend,Simon Khagi,D Lovick,Jana Portnow,Lyndon Kim,William G Loudon,Nina L. Martinez,Reid C. Thompson,David Avigan,Karen Fink,Francois J. Geoffroy,Pierre Giglio,Oleg Gligich,Dietmar Krex,Scott Lindhorst,Jose Lutzky,Hans Joerg Meisel,Minou Nadji-Ohl,L. Sanchin,Andrew E. Sloan,Lynne P. Taylor,Julian K. Wu,Erin M. Dunbar,Arnold B. Etame,Santosh Kesari,David Mathieu,David Piccioni,David S. Baskin,Michel Lacroix,Sven-Axel May,Pamela New,Timothy J. Pluard,Steven A. Toms,Victor Tse,Scott Peak,John L. Villano,James Battiste,Paul Mulholland,Michael Pearlman,Kevin Petrecca,Michael Schulder,Robert M. Prins,Alton L. Boynton,Marnix L. Bosch +72 more
TL;DR: In this article , treatment with autologous tumor lysate-loaded dendritic cell vaccination (DCVax-L) was associated with improved overall survival (OS) for patients with newly diagnosed glioblastoma (nGBM) and recurrent gliomatosis (rGBM), compared with standard of care (SOC).
A Systematic Framework to Rapidly Obtain Data on Patients with Cancer and COVID-19: CCC19 Governance, Protocol, and Quality Assurance.
Maheen Z. Abidi,David M. Aboulafia,Melissa K. Accordino,Jared D. Acoba,Manmeet Ahluwalia,Syed A. Ahmad,Archana Ajmera,Saif I. Alimohamed,Jessica K. Altman,Anne H. Angevine,Ziad Bakouny,Michael H. Bar,Aditya Bardia,Jill S. Barnholtz-Sloan,Briana Barrow McCollough,Babar Bashir,Gerald Batist,Tanios Bekaii-Saab,Stephanie Berg,Eric H. Bernicker,Divaya Bhutani,Mehmet Asim Bilen,Poorva Bindal,Rohit Bishnoi,Sibel Blau,Pamela Bohachek,Genevieve M. Boland,Mark Bonnen,Gabrielle Bouchard,Nathaniel Bouganim,Daniel W. Bowles,Fiona Busser,Omar Butt,Angelo Cabal,Wilhelmina D. Cabalona,Elwyn C. Cabebe,Paolo Caimi,Jian Campian,Theresa M. Carducci,James L. Chen,Alex Cheng,David D. Chism,Toni K. Choueiri,Melanie J. Clark,Jessica M. Clement,Jean M. Connors,Erin Cook,Catherine Curran,Ahmad Daher,Mark E. Dailey,Elizabeth J. Davis,Scott J. Dawsey,John F. Deeken,Salvatore Del Prete,George D. Demetri,Aakash Desai,Deborah B. Doroshow,Eric B. Durbin,Pamela C Egan,Rawad Elias,Arielle Elkrief,Arielle Elkrief,Destry J. Elms,Amro Elshoury,Bryan A. Faller,Dimitrios Farmakiotis,Leslie A. Fecher,Lawrence E. Feldman,Cristiano Ferrario,Mark A. Fiala,Daniel Blake Flora,Benjamin French,Christopher R. Friese,Julie C. Fu,Shirish M. Gadgeel,Justin F. Gainor,Matthew D. Galsky,Gerald Gantt,Jorge A. Garcia,Benjamin A. Gartrell,Margaret E. Gatti-Mays,David Gill,Erin A. Gillaspie,Antonio Giordano,Grace Glace,Michael Glover,Sanjay Goel,Jerome J. Graber,Elizabeth A. Griffiths,Petros Grivas,Punita Grover,Anthony P. Gulati,Shuchi Gulati,Shilpa Gupta,Michael J. Gurley,Navid Hafez,Susan Halabi,Thorvardur R. Halfdanarson,Balazs Halmos,Daniel J. Hausrath,Jessica Hawley,Cassandra Hennessy,Roy S. Herbst,Dawn L. Hershman,Claire Hoppenot,Kent Hoskins,Irma Hoyo-Ulloa,Emily Hsu,Chih-Yuan Hsu,Clara Hwang,Jessica Yasmine Islam,Salma K. Jabbour,Chinmay Jani,Alokkumar Jha,Sachin R. Jhawar,Douglas B. Johnson,Monika Joshi,Anup Kasi,Kaitlin M. Kelleher,Hagen F. Kennecke,Ali Raza Khaki,Hina Khan,Mahir Khan,Jordan Kharofa,Goetz Kloecker,Jeanna Knoble,Amit Kulkarni,Vaibhav Kumar,Philip E. Lammers,John C. Leighton,Christopher Lemmon,Mark A. Lewis,Ang Li,X. Li,Stephen V. Liu,K.M. Lo,Arturo Loaiza-Bonilla,Barbara Logan,Elizabeth T. Loggers,Gilberto Lopes,Jonathan M. Loree,Patricia LoRusso,Clarke A. Low,Maryam B. Lustberg,Gary H. Lyman,Ryan C. Lynch,Subha Madhavan,Daruka Mahadevan,Sana Z. Mahmood,Abdul-Hai Mansoor,Michelle Marcum,Merry Jennifer Markham,Sandeep H. Mashru,Tyler Masters,Blanche Mavromatis,Rana R. McKay,Christopher McNair,Shannon K. McWeeney,Alvaro G. Menendez,Harry Menon,Ruben A. Mesa,Vasil Mico,Chaim Miller,Sanjay Mishra,Ryan Monahan,Alicia K. Morgans,Mary F. Mulcahy,Daniel Mundt,Sarah Mushtaq,Gayathri Nagaraj,Sarah Nagle,Elizabeth S. Nakasone,John M. Nakayama,Heather H. Nelson,Eneida R. Nemecek,Ryan H. Nguyen,Amanda Nizam,Anju Nohria,Pier Vitale Nuzzo,Nitin Ohri,Adam J. Olszewski,Susie Owenby,Corrie A. Painter,Joshua D. Palmer,Orestis A. Panagiotou,Cathleen Park,Mary M. Pasquinelli,Jaymin M. Patel,Kanishka G. Patel,Prakash Peddi,Nathan A. Pennell,Solange Peters,Christine Pilar,Clement Pillainayagam,Matthew Puc,Amelie G. Ramirez,Joerg Rathmann,Deepak Ravindranathan,Sonya A. Reid,Daniel Y. Reuben,Sanjay G. Revankar,Kerry L. Reynolds,Young Soo Rho,Terence Duane Rhodes,Robert L. Rice,Jonathan Riess,Brian I. Rini,Cameron Rink,Lane R. Rosen,Lori J. Rosenstein,Rachel P. Rosovsky,Bertrand Routy,Marc A. Rovito,Samuel M. Rubinstein,M. Wasif Saif,Mary Salazar,Miriam Santos Dutra,Lidia Schapira,Andrew Schmidt,Brett A. Schroeder,Gary K. Schwartz,Candice Schwartz,Michael T. Schweizer,Oscar K. Serrano,Danielle A. Shafer,Pankil Shah,Dimpy P. Shah,Mansi R. Shah,Sumit A. Shah,Chintan Shah,Grace Shaw,Justin Shaya,Yu Shyr,David A. Slosky,Melissa Smits,Carmen C. Solorzano,Karen Stauffer,Keith Stockerl-Goldstein,Daniel G. Stover,Jamie Stratton,Catherine Stratton,Mitrianna Streckfuss,Suki Subbiah,Lisa Tachiki,Eyob Tadesse,Michael A. Thompson,Umit Topaloglu,Matthew D Tucker,Eliezer M. Van Allen,Susan Van Loon,Karen Vega-Luna,Neeta K. Venepalli,Amit Verma,Praveen Vikas,Shaveta Vinayak,Donald C. Vinh,Michael J. Wagner,Sarah Wall,Lucy L. Wang,Jeremy L. Warner,Firas Wehbe,Paul L. Weinstein,Matthias Weiss,Lisa Weissmann,Tanya M. Wildes,Nicole Williams,Trisha Wise-Draper,William A. Wood,Julie Tsu-Yu Wu,Elizabeth Marie Wulff-Burchfield,Zhuoer Xie,Wenxin Xu,Albert C. Yeh,Irene S. Yu,Peter Paul Yu,Rosemary Zacks,Qamar Ul Zaman,Howard Zaren,Tian Zhang,Alice Zhou,Huili Zhu,Rebecca L. Zon,Leyre Zubiri +282 more
TL;DR: Future directions include increased electronic health record integration for direct data ingestion, expansion to additional domestic and international sites, more intentional patient involvement, and granular analyses of still-unanswered questions related to cancer subtypes and treatments.
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Correction: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma [J Transl Med., 16, (2018) (142)] DOI: 10.1186/s12967-018-1507-6
Linda M. Liau,Keyoumars Ashkan,David Tran,Jian Campian,John E. Trusheim,Charles S. Cobbs,Jason Heth,Michael Salacz,Sarah A. Taylor,Stacy D. D’Andre,Fabio M. Iwamoto,Edward J. Dropcho,Yaron A. Moshel,Kevin A. Walter,Clement Pillainayagam,Robert Aiken,Rekha Chaudhary,Samuel Goldlust,Daniela A. Bota,Paul Duic,Jai Grewal,Heinrich Elinzano,Steven A. Toms,Kevin O. Lillehei,Tom Mikkelsen,Tobias Walbert,Steven R. Abram,Andrew Brenner,Steven Brem,Matthew G. Ewend,Simon Khagi,Jana Portnow,Lyndon Kim,William G. Loudon,Reid C. Thompson,David Avigan,Karen Fink,Francois J. Geoffroy,Scott Lindhorst,Jose Lutzky,Andrew E. Sloan,Gabriele Schackert,Dietmar Krex,Hans Jorg Meisel,Julian Wu,Raphael P. Davis,Christopher Duma,Arnold B. Etame,David Mathieu,Santosh Kesari,David Piccioni,Manfred Westphal,David S. Baskin,Pamela Z. New,Michel Lacroix,Sven Axel May,Timothy J. Pluard,Victor Tse,Richard M. Green,John L. Villano,Michael Pearlman,Kevin Petrecca,Michael Schulder,Lynne Taylor,Anthony E. Maida,Robert M. Prins,Timothy F. Cloughesy,Paul Mulholland,Marnix L. Bosch +68 more
TL;DR: This Correction corrects an error in the spelling of one of the author names and correct versions of the affected sentence are indicated.
Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma
H. Perlow,Alexander Yaney,Michael Yang,Brett Klamer,J. Matsui,Raju R. Raval,Dukagjin Blakaj,Andrea L. Arnett,Sasha Beyer,James B. Elder,Mario Ammirati,Russell R. Lonser,Douglas A. Hardesty,Shirley Ong,Pierre Giglio,Clement Pillainayagam,J. Goranovich,John C. Grecula,Arnab Chakravarti,Vinai Gondi,D. D. Brown,Joshua D. Palmer +21 more
TL;DR: Isoeffective dosing to 52.5 Gy in 15 fractions was associated with superior OS compared to standard of care 40 Gy with temozolomide, and hypothesis generating data support accelerated hypofractionation in future prospective trials.
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