Claudia Martini
University of Pisa
530 Papers
4.7K Citations
Claudia Martini is an academic researcher from University of Pisa. The author has contributed to research in topics: Adenosine receptor & Receptor. The author has an hindex of 49, co-authored 527 publications. Previous affiliations of Claudia Martini include University of Ferrara & University of Florence.
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Papers
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor
Paolo Ciana,Marta Fumagalli,Maria Letizia Trincavelli,Claudia Verderio,Patrizia Rosa,Davide Lecca,Silvia Ferrario,Chiara Parravicini,Valérie Capra,Paolo Gelosa,Uliano Guerrini,Silvia Belcredito,Mauro Cimino,Luigi Sironi,Elena Tremoli,G. Enrico Rovati,Claudia Martini,Maria P. Abbracchio +17 more
TL;DR: GPR17, a Gi‐coupled orphan receptor at intermediate phylogenetic position between P2Y and CysLT receptors, is specifically activated by both families of endogenous ligands, leading to both adenylyl cyclase inhibition and intracellular calcium increases, which may lead to dualistic drugs of previously unexplored therapeutic potential.
439
Oxytocin receptor polymorphisms and adult attachment style in patients with depression.
Barbara Costa,Stefano Pini,P Gabelloni,Marianna Abelli,Lisa Lari,Alessandra Cardini,Matteo Muti,Camilla Gesi,Stefano Landi,Silvana Galderisi,Armida Mucci,Antonio Lucacchini,Giovanni B. Cassano,Claudia Martini +13 more
TL;DR: Findings support the involvement of the oxytocinergic system in the mechanisms that underlie depression and specific adult attachment styles.
282
The oxysterol–CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils
Laura Raccosta,Raffaella Fontana,Daniela Maggioni,Claudia Lanterna,Eduardo J. Villablanca,Aida Paniccia,Andrea Musumeci,Elena Chiricozzi,Maria Letizia Trincavelli,Simona Daniele,Claudia Martini,Jan-Åke Gustafsson,Jan-Åke Gustafsson,Claudio Doglioni,Safiyè Gonzalvo Feo,Andrea Leiva,Maria Grazia Ciampa,Laura Mauri,Cristina Sensi,Alessandro Prinetti,Ivano Eberini,J. Rodrigo Mora,Claudio Bordignon,Claudio Bordignon,Knut R. Steffensen,Sandro Sonnino,Silvano Sozzani,Catia Traversari,Vincenzo Russo +28 more
TL;DR: Tumor-derived oxysterols recruit protumor neutrophils in an LXR-independent, CXCR2-dependent manner, thus favoring tumor growth by promoting neoangiogenesis and immunosuppression.
Phenotypic changes, signaling pathway and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation
Marta Fumagalli,Simona Daniele,Davide Lecca,Philip R. Lee,Chiara Parravicini,R. Douglas Fields,Patrizia Rosa,Flavia Antonucci,Claudia Verderio,M. Letizia Trincavelli,Placido Bramanti,Claudia Martini,Maria P. Abbracchio +12 more
TL;DR: GPR17 is a new marker of these transition stages of NG2+ OPCs and point to uracil nucleotides and cysLTs as main extrinsic local regulators of these cells under physiological conditions and during myelin repair.
176