Clarissa Stephanie Santoso
Boston University
13 Papers
16 Citations
Clarissa Stephanie Santoso is an academic researcher from Boston University. The author has contributed to research in topics: Biology & Transcriptional regulation. The author has an hindex of 4, co-authored 10 publications.
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Papers
Global landscape of mouse and human cytokine transcriptional regulation
Sebastian Carrasco Pro,Alvaro Dafonte Imedio,Clarissa Stephanie Santoso,Kok Ann Gan,Jared A. Sewell,Melissa Martinez,Rebecca Sereda,Shivani Mehta,Juan I. Fuxman Bass +8 more
TL;DR: A comprehensive database, CytReg, is mined through three decades of studies to generate a framework for the rational design of future cytokine gene regulation studies, and shows a correlation between TF connectivity and immune phenotype and disease.
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Comprehensive mapping of the human cytokine gene regulatory network.
Clarissa Stephanie Santoso,Zhaorong Li,Sneha Lal,Samson Yuan,Kok Ann Gan,Luis M. Agosto,Xing Liu,Sebastian Carrasco Pro,Jared A. Sewell,Andrew J. Henderson,Maninjay K. Atianand,Juan I. Fuxman Bass +11 more
TL;DR: In this paper, the authors used enhanced yeast one-hybrid (eY1H) assays to derive a comprehensive network comprising 1380 interactions between 265 transcription factors and 108 cytokine gene promoters.
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The ABC Transporter Eato Promotes Cell Clearance in the Drosophila melanogaster Ovary.
Clarissa Stephanie Santoso,Tracy L. Meehan,Jeanne S. Peterson,Tiara M. Cedano,Christopher V. Turlo,Kimberly McCall +5 more
TL;DR: Eato is identified as the ced-7/ABCA1 ortholog in D. melanogaster, and a role for Eato is demonstrated in Drpr accumulation and phagocytic membrane extensions during NC clearance in the ovary.
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Therapeutic Targeting of Transcription Factors to Control the Cytokine Release Syndrome in COVID-19
Clarissa Stephanie Santoso,Zhaorong Li,Jaice T. Rottenberg,Xing Liu,Vivian X. Shen,Juan I. Fuxman Bass +5 more
TL;DR: In this paper, the authors integrated a resource of TF-cytokine gene interactions with single-cell RNA-seq expression data from bronchoalveolar lavage fluid cells of COVID-19 patients to identify candidate transcription factors (TFs) for therapeutic targeting using approved drugs.
In vitro Targeting of Transcription Factors to Control the Cytokine Release Syndrome in COVID-19
Clarissa Stephanie Santoso,Zhaorong Li,Jaice T. Rottenberg,Xing Liu,Vivian X. Shen,Juan I. Fuxman Bass +5 more
TL;DR: In this paper, the authors integrated a resource of TF-cytokine gene interactions with single-cell RNA-seq expression data from bronchoalveolar lavage fluid cells of COVID-19 patients to identify candidate transcription factors (TFs) for therapeutic targeting using approved drugs.