This document updates and expands the initial Infectious Diseases Society of America (IDSA) Fever and Neutropenia Guideline that was published in 1997 and first updated in 2002. It is intended as a guide for the use of antimicrobial agents in managing patients with cancer who experience chemotherapy-induced fever and neutropenia. Recent advances in antimicrobial drug development and technology, clinical trial results, and extensive clinical experience have informed the approaches and recommendations herein. Because the previous iteration of this guideline in 2002, we have a developed a clearer definition of which populations of patients with cancer may benefit most from antibiotic, antifungal, and antiviral prophylaxis. Furthermore, categorizing neutropenic patients as being at high risk or low risk for infection according to presenting signs and symptoms, underlying cancer, type of therapy, and medical comorbidities has become essential to the treatment algorithm. Risk stratification is a recommended starting point for managing patients with fever and neutropenia. In addition, earlier detection of invasive fungal infections has led to debate regarding optimal use of empirical or preemptive antifungal therapy, although algorithms are still evolving. What has not changed is the indication for immediate empirical antibiotic therapy. It remains true that all patients who present with fever and neutropenia should be treated swiftly and broadly with antibiotics to treat both gram-positive and gram-negative pathogens. Finally, we note that all Panel members are from institutions in the United States or Canada; thus, these guidelines were developed in the context of North American practices. Some recommendations may not be as applicable outside of North America, in areas where differences in available antibiotics, in the predominant pathogens, and/or in health care-associated economic conditions exist. Regardless of venue, clinical vigilance and immediate treatment are the universal keys to managing neutropenic patients with fever and/or infection.

/pdf/clinical-practice-guideline-for-the-use-of-antimicrobial-1cdrjevze2.pdf

Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America

Bevacizumab plus Irinotecan,Fluorouracil,and Leucovorin for Metastatic Colorectal Cancer

/pdf/executive-summary-clinical-practice-guideline-for-the-use-of-4f3cim4eam.pdf

Executive Summary: Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America

Procedure Appropriateness Category Relative Radiation Level Radiography area of interest Usually Appropriate Varies CT area of interest with IV contrast Usually Not Appropriate Varies CT area of interest without and with IV contrast Usually Not Appropriate Varies CT area of interest without IV contrast Usually Not Appropriate Varies FDG-PET/CT whole body Usually Not Appropriate ☢☢☢☢ MRI area of interest without and with IV contrast Usually Not Appropriate O MRI area of interest without IV contrast Usually Not Appropriate O Bone scan whole body Usually Not Appropriate ☢☢☢ US area of interest Usually Not Appropriate O

The American College of Radiology. ACR Appropriateness Criteria project.

Andreas Sturm,a Christian Maaser,b Emma Calabrese,c Vito Annese,d Gionata Fiorino,e Torsten Kucharzik,f Stephan R. Vavricka,g Bram Verstockt,h, Patrick van Rheenen,i Damian Tolan,j Stuart A. Taylor,k Jordi Rimola,l Florian Rieder,m Jimmy K. Limdi,n Andrea Laghi,o Eduards Krustiņš,p Paulo G. Kotze,q Uri Kopylov,r Konstantinos Katsanos,s Steve Halligan,t Hannah Gordon,u Yago González Lama,v Pierre Ellul,w Rami Eliakim,r Fabiana Castiglione,x Johan Burisch,y, Paula Borralho Nunes,z, Dominik Bettenworth,aa Daniel C. Baumgart,bb Jaap Stoker,cc on behalf of the European Crohn’s and Colitis Organisation [ECCO] and the European Society of Gastrointestinal and Abdominal Radiology [ESGAR]

https://www.zora.uzh.ch/id/eprint/181192/1/2018_05_02_Manuscript2_ECCO_ESGAR-DiagnosticsGL_c4-5.pdf

Ecco-esgar guideline for diagnostic assessment in ibd part 2: Ibd scores and general principles and technical aspects

OBJECTIVE. Retroperitoneal fibrosis is a rare collagen vascular disorder of unclear cause. Both benign and malignant associations have been described, rendering differentiation of these entities of paramount importance because sinister pathology alters the diagnosis. Thus, a high level of diligence is required in the investigation of this condition, particularly in patients with concomitant systemic conditions.CONCLUSION. Familiarity with the realm of imaging manifestations of retroperitoneal fibrosis is vital to ensure correct diagnosis and optimal treatment.

Retroperitoneal fibrosis: a review of clinical features and imaging findings.

Normal small bowel wall characteristics on MR enterography.

OBJECTIVE. The objective of our study was to evaluate the morphologic appearances of small-bowel lymphoma using MR enterography to identify key morphologic traits capable of providing an association between imaging manifestations and likely histologic diagnosis.MATERIALS AND METHODS. Over a 54-month period, 10 patients with subsequently confirmed small-bowel lymphoma were imaged using a standardized MR enterography technique. Retrospective chart review was performed to detect associated disease processes, such as celiac disease. The morphologic characteristics of each segment with lymphomatous involvement were evaluated with respect to tumor location, tumor size, mural characteristics, fold features, loop dilatation, luminal stricturing, mesenteric or antimesenteric distribution, mesenteric involvement, and signal intensity.RESULTS. Nineteen distinct segments of lymphomatous involvement were identified in 10 patients, and underlying celiac disease was confirmed in six of the 10 patients. This patient grou...

https://www.ajronline.org/doi/pdf/10.2214/AJR.07.2721

MR Enterography of Small- Bowel Lymphoma: Potential for Suggestion of Histologic Subtype and the Presence of Underlying Celiac Disease

CT evaluation of Chamberlain's, McGregor's, and McRae's skull-base lines

Pseudoaneurysm of the uterine artery after abdominal hysterectomy: radiologic diagnosis and management.

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