Clara Moon
Washington University in St. Louis
7 Papers
35 Citations
Clara Moon is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Intestinal mucosa & Biology. The author has an hindex of 7, co-authored 7 publications.
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Papers
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells
Brian T. Edelson,Wumesh Kc,Richard Juang,Masako Kohyama,Loralyn A. Benoit,Paul A. Klekotka,Clara Moon,Jörn C. Albring,Wataru Ise,Drew G. Michael,Deepta Bhattacharya,Thaddeus S. Stappenbeck,Michael J. Holtzman,Sun-Sang J. Sung,Theresa L. Murphy,Kai Hildner,Kenneth M. Murphy +16 more
TL;DR: Evidence is provided for a developmental relationship between lymphoid organ–resident CD8α+ cDCs and nonlymphoid CD103+ DCs and their shared developmental dependence on the transcription factor Irf8.
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Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays
Kelli L. VanDussen,Jeffrey M. Marinshaw,Nurmohammad Shaikh,Hiroyuki Miyoshi,Clara Moon,Phillip I. Tarr,Matthew A. Ciorba,Thaddeus S. Stappenbeck +7 more
TL;DR: A large panel of human gastrointestinal epithelial cell lines from patient biopsies taken during routine upper and lower endoscopy procedures are created to facilitate the study of interindividual, functional studies of human intestinal epithelial cells, including host–microbial interactions.
485
Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner
Matthew A. Ciorba,Terrence E. Riehl,M. Suprada Rao,Clara Moon,Xueping Ee,Gerardo M. Nava,Monica R. Walker,Jeffrey M. Marinshaw,Thaddeus S. Stappenbeck,William F. Stenson +9 more
TL;DR: LGG or its CM reduce radiation-induced epithelial injury and improve crypt survival and a TLR-2/MyD88 signalling mechanism leading to repositioning of constitutive COX-2-expressing mesenchymal stem cells to the crypt base is invoked.
263
Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation
Clara Moon,Megan T. Baldridge,Meghan A. Wallace,Carey-Ann D. Burnham,Herbert W. Virgin,Thaddeus S. Stappenbeck +5 more
TL;DR: Faecal IgA is proposed as one marker of microbial variability and co-housing and/or faecal transplantation enables analysis of progeny from different dams and it is found that bacteria from IgA-low mice degrade the secretory component of secretory IgA as well as IgA itself.
Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis
TL;DR: The recently developed method for the culture of intestinal epithelial spheroids is adapted to establish primary epithelial cell monolayers from the colon of multiple genetic mouse strains, allowing the use of primary cells for studies of intestinal physiology.
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