Clairice Pearce
University of Minnesota
9 Papers
5 Citations
Clairice Pearce is an academic researcher from University of Minnesota. The author has contributed to research in topics: Oncolytic virus & Regenerative medicine. The author has an hindex of 3, co-authored 8 publications.
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Papers
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Andrew S. Mendiola,Zhaoqi Yan,Karuna Dixit,Jeffrey R. Johnson,Mehdi Bouhaddou,Anke Meyer-Franke,Min-Gyoung Shin,Ayushi Agrawal,Eilidh MacDonald,Gayathri Muthukumar,Clairice Pearce,Belinda S. Cabriga,Rosa Meza-Acevedo,Maria del pilar Alzamora,Scott S. Zamvil,Alexander R. Pico,Jae K. Ryu,Nevan J. Krogan,Katerina Akassoglou +18 more
TL;DR: In this article , the authors established an unbiased blood-innate immunity multiomic and genetic loss-of-function pipeline to define the transcriptome and global phosphoproteome of blood-induced innate immune polarization and its role in microglia neurotoxicity.
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Interspecies Organogenesis for Human Transplantation
Andrew T. Crane,Rajagopal N. Aravalli,Atsushi Asakura,Andrew W. Grande,Venkatramana D. Krishna,Daniel F. Carlson,Maxim C.-J. Cheeran,Georgette Danczyk,James R. Dutton,Perry B. Hackett,Wei Shou Hu,Ling Li,Wei Cheng Lu,Zachary D. Miller,Timothy O'Brien,Angela Panoskaltsis-Mortari,Ann M. Parr,Clairice Pearce,Mercedes Ruiz-Estévez,Maple Shiao,Christopher J. Sipe,Nikolas G. Toman,Joseph P. Voth,Hui Xie,Clifford J. Steer,Walter C. Low +25 more
TL;DR: This review will focus on the pancreas, liver, heart, kidney, lung, and skeletal muscle, as well as cells of the immune and nervous systems, and identifies and discusses the common causes of organ failure and the current state of regenerative therapies.
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Orientation selective deep brain stimulation of the subthalamic nucleus in rats.
Lauri J. Lehto,Antonietta Canna,Lin Wu,Alejandra Sierra,Ekaterina Zhurakovskaya,Jun Ma,Clairice Pearce,Maple Shaio,Pavel Filip,Matthew D. Johnson,Walter C. Low,Olli Gröhn,Heikki Tanila,Silvia Mangia,Shalom Michaeli +14 more
TL;DR: OS-DBS offers an additional degree of flexibility for optimization of DBS of the STN which may enable a better treatment response, and is concluded to be a promising addition to DBS technology enabling better control of the stimulating electric field.
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Zika virus-based immunotherapy enhances long-term survival of rodents with brain tumors through upregulation of memory T-cells
Andrew T. Crane,Matthew R. Chrostek,Venkatramana D. Krishna,Maple Shiao,Nikolas G. Toman,Clairice Pearce,Sarah K. Tran,Christopher J. Sipe,Winston L. Guo,Joseph P. Voth,Shivanshi Vaid,Hui Xie,Wei Cheng Lu,Will Swanson,Andrew W. Grande,Mark R. Schleiss,Craig J. Bierle,Maxim C.-J. Cheeran,Walter C. Low +18 more
TL;DR: It is suggested that ZIKV can serve as an adjuvant to subcutaneous tumor vaccines that enhance long-term survival and generate protective tissue-resident memory CD4+ T-cells.
The Bioengineering of Exogenic Organs and/or Cells for Use in Regenerative Medicine
Rajagopal N. Aravalli,Maple Shiao,Wei Cheng Lu,Hui Xie,Clairice Pearce,Nikolas G. Toman,Georgette Danczyk,Christopher J. Sipe,Zachary D. Miller,Andrew T. Crane,Joseph P. Voth,Walter C. Low,Clifford J. Steer +12 more
- 01 Jan 2018
TL;DR: It will be imperative to understand the underlying conditions for stem cell growth in a developmental environment, to determine if cross-species chimeras can be therapeutically developed and have a critical role for precision medicine.
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