Claire Béraud
French Institute of Health and Medical Research
15 Papers
89 Citations
Claire Béraud is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Clear cell renal cell carcinoma & Tumor suppressor gene. The author has an hindex of 7, co-authored 10 publications. Previous affiliations of Claire Béraud include University of Strasbourg.
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Papers
Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors.
Natacha Rochel,Clémentine Krucker,L. Coutos-Thevenot,L. Coutos-Thevenot,Judit Osz,R. Zhang,R. Zhang,R. Zhang,E. Guyon,E. Guyon,W. Zita,S. Vanthong,O.A. Hernandez,Maxime Bourguet,K.A. Badawy,Florent Dufour,Florent Dufour,Carole Peluso-Iltis,S. Heckler-Beji,Annick Dejaegere,Aurélie Kamoun,A. De Reynies,Yann Neuzillet,Yann Neuzillet,Sandra Rebouissou,Sandra Rebouissou,Sandra Rebouissou,Claire Béraud,Hervé Lang,Thierry Massfelder,Yves Allory,Yves Allory,Sarah Cianférani,Roland H. Stote,F. Radvanyi,F. Radvanyi,Isabelle Bernard-Pierrot,Isabelle Bernard-Pierrot +37 more
TL;DR: Genomic alterations of PPARG that lead to pro-tumorigenic PPARγ/RXRα pathway activation in luminal bladder tumors are revealed and may open the way towards alternative options for treatment.
53
Vitamin D3 triggers antitumor activity through targeting hedgehog signaling in human renal cell carcinoma
Valérian Dormoy,Claire Béraud,Véronique Lindner,Catherine Coquard,Mariette Barthelmebs,David Brasse,Didier Jacqmin,Hervé Lang,Thierry Massfelder +8 more
TL;DR: It is established that, although VD3 receptors and metabolizing enzymes are absent in CCC, cholecalciferol supplementation is a strong tool to block the reactivation of SHH-Gli pathway in this pathology, leading ultimately to tumor regression.
LIM-class homeobox gene Lim1, a novel oncogene in human renal cell carcinoma.
Valérian Dormoy,Claire Béraud,Véronique Lindner,Lionel Thomas,Catherine Coquard,Mariette Barthelmebs,Didier Jacqmin,Hervé Lang,Thierry Massfelder +8 more
TL;DR: It is established that the developmental marker Lim1 acts as an oncogene in cancer cells and targeting Lim1 may constitute an innovative therapeutic intervention in human CCC.
38
Targeting FAK scaffold functions inhibits human renal cell carcinoma growth
Claire Béraud,Valérian Dormoy,Sabrina Danilin,Véronique Lindner,Audrey Bethry,Mazène Hochane,Catherine Coquard,Mariette Barthelmebs,Didier Jacqmin,Hervé Lang,Thierry Massfelder +10 more
TL;DR: The findings reveal a previously uncharacterized role of FAK in CCC whereby FAK exerts oncogenic properties through a non canonical signaling pathway involving its scaffolding kinase‐independent properties, and targeting the FAK scaffold may represent a promising approach for developing innovative and highly specific therapies in human CCC.
36
Parathyroid hormone-related protein modulates inflammation in mouse mesangial cells and blunts apoptosis by enhancing COX-2 expression.
Mazène Hochane,Denis Raison,Catherine Coquard,Claire Béraud,Audrey Bethry,Sabrina Danilin,Thierry Massfelder,Mariette Barthelmebs +7 more
TL;DR: Findings suggest that PTHrP functions as a booster of glomerular inflammatory processes and may be a negative feedback loop preserving MC survival.
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