Ciaran P. Kelly
Beth Israel Deaconess Medical Center
360 Papers
1.8K Citations
Ciaran P. Kelly is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Clostridium difficile & Medicine. The author has an hindex of 81, co-authored 334 publications. Previous affiliations of Ciaran P. Kelly include Trinity College, Dublin & Boston University.
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Papers
Health care costs and mortality associated with nosocomial diarrhea due to Clostridium difficile.
TL;DR: A conservative estimate of the cost of this disease in the United States exceeds $1.1 billion per year after adjustment for age, comorbidity, and disease severity.
The incidence and clinical spectrum of refractory celiac disease in a north american referral center.
Bakht Roshan,Daniel A. Leffler,Shailaja Jamma,Melinda Dennis,Sunil A Sheth,Kenneth R. Falchuk,Robert M. Najarian,Jeff Goldsmith,Sohaib Tariq,Detlef Schuppan,Ciaran P. Kelly +10 more
TL;DR: Although RCD is a serious condition with significant morbidity; the observed mortality rates are low in the population; this study suggests that RCD may be less severe in North American vs. European populations.
Human colonic aspirates containing immunoglobulin A antibody to Clostridium difficile toxin A inhibit toxin A-receptor binding.
TL;DR: It is suggested that human colonic IgA antitoxin may protect against C. difficile colitis by inhibiting the binding of toxin A to its intestinal epithelial cell receptor.
MIP-3α neutralizing monoclonal antibody protects against TNBS-induced colonic injury and inflammation in mice
TL;DR: Findings indicate that blockade of MIP-3alpha bioactivity can significantly reduce TNBS-mediated colonic injury and T cell recruitment, suggesting a role for this chemokine in the pathophysiology of intestinal inflammation.