Chunxia Zhou
Peking Union Medical College
26 Papers
176 Citations
Chunxia Zhou is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Immunotherapy & Immune system. The author has an hindex of 12, co-authored 26 publications.
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Papers
Spheres derived from the human SK-RC-42 renal cell carcinoma cell line are enriched in cancer stem cells.
Yong Zhong,Kaopeng Guan,Sujuan Guo,Chunxia Zhou,Dongmei Wang,Wenbo Ma,Youhui Zhang,Changling Li,Shuren Zhang +8 more
TL;DR: It is demonstrated that a subpopulation of SK-RC-42 cells were capable of growing as tumor spheres in serum-free medium supplemented with EGF and bFGF, indicating that CSCs can be enriched from RCC by culturing the tumor cells as spheres.
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Repeated cycles of 5-fluorouracil chemotherapy impaired anti-tumor functions of cytotoxic T cells in a CT26 tumor-bearing mouse model
TL;DR: It is found that mice treated with cytokine induced killer cells and PD-L1 monoclonal antibodies after one cycle of 5-FU had a better anti-tumor performance than those treated with chemotherapy or immunotherapy alone, pointing towards early implementation of immunotherapy to improve the anti-Tumor effect.
Enhancement of antitumour immunity by a novel chemotactic antigen DNA vaccine encoding chemokines and multiepitopes of prostate-tumour-associated antigens
TL;DR: It is demonstrated that vaccination with pSLC‐3P‐Fc by gene gun inoculation induced a strong antitumour response in a mouse tumour model, which significantly inhibited tumour growth and prolonged the survival time of the tumour‐bearing mice.
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Granzyme M expressed by tumor cells promotes chemoresistance and EMT in vitro and metastasis in vivo associated with STAT3 activation
Huiru Wang,Qing Sun,Yanhong Wu,Lin Wang,Chunxia Zhou,Wenbo Ma,Youhui Zhang,Shengdian Wang,Shuren Zhang +8 more
TL;DR: The role of granzyme M expressed by tumor in chemoresistance, invasion, metastasis and EMT is revealed, which facilitated tumor growth and metastasis in vivo.
Cancer stem cells sustaining the growth of mouse melanoma are not rare.
TL;DR: It is reported that the growth of B16-F10 melanoma cells in syngeneic mice could be maintained by a relatively larger proportion of tumor cells, suggesting that cancer stem cells responsible for the sustainable growth of tumor are rare.
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