Chunnian He
Peking Union Medical College
76 Papers
214 Citations
Chunnian He is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 15, co-authored 56 publications. Previous affiliations of Chunnian He include Chinese Ministry of Education.
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Papers
Saikosaponin-D Prevents Acute Renal Injury via Inhibition of NLRP3 Inflammasome By SIRT1
Lin Kang,Fan Yang,Xiu-zhi Zhang,Jing-Tai Zhao,Yang Liu,Huan-fen Zhao,Zhijuan Hu,Bing Liu,Chunnian He +8 more
TL;DR: Sikosaponin-d (SSD) reduced kidney injury and inflammation, induced SIRT1, and suppressed protein expression on in vivo mice model of acute kidney injury (AKI) and these findings confirm that SSD prevents AKI via inhibition of NLRP3 inflammasome by SIRT 1.
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Integrating network pharmacology analysis and pharmacodynamic evaluation for exploring the active components and molecular mechanism of moutan seed coat extract to improve cognitive impairment
TL;DR: Screening the pharmacodynamic components in PSCE indicated that PSCE and SB might be potential anti-AD drug candidates, providing a scientific basis for the development and utilization of Moutan bark.
1
Patent
New furanditerpenoid compound, preparation method and application thereof
Bing Peng,Pei-Gen Xiao,Yong Peng,Wei Xiao,Chunnian He,Lijia Xu +5 more
- 01 Dec 2010
TL;DR: In this article, a furanditerpenoid compound with a brand new structure separated from Saururaceae medical plants, a preparation method and an application thereof was described, and experimental results showed that the compound has a protective function for endothelial injury caused by H2O2, and can prevent and cure cardiovascular and cerebrovascular diseases.
1
•Journal Article
The isolation and structure identification of triptotriterpenic acid C
TL;DR: A new ursolic-type acid named triptotriterpenic acid C was obtained from the total glycosides extracted from the root of Tripterygium wilfordii Hook by X-ray crystallo-diffraction analysis of its methyl ester.
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Saikosaponin-D Prevents Acute Renal Injury via Inhibition of NLRP3 Inflammasome By SIRT1
Lin Kang,Fan Yang,Xiu-zhi Zhang,Jing Zhao,Yang Liu,Huan-fen Zhao,Zhijuan Hu,Bing Liu,Chunnian He +8 more
TL;DR: Sikosaponin-d (SSD) reduced kidney injury and inflammation, induced SIRT1, and suppressed protein expression on in vivo mice model of acute kidney injury (AKI) and these findings confirm that SSD prevents AKI via inhibition of NLRP3 inflammasome by SIRT 1.
1