Chun Li
Peking Union Medical College
42 Papers
136 Citations
Chun Li is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 36 publications.
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Papers
Systematic evaluation of structure-activity relationships of the riminophenazine class and discovery of a C2 pyridylamino series for the treatment of multidrug-resistant tuberculosis.
Binna Liu,Kai Liu,Yu Lu,Dongfeng Zhang,Tianming Yang,Xuan Li,Chen Ma,Meiqin Zheng,Bin Wang,Gang Zhang,Fei Wang,Zhenkun Ma,Chun Li,Haihong Huang,Dali Yin +14 more
TL;DR: The study reveals that the central tricyclic phenazine system and the pendant aromatic rings are important for anti-tuberculosis activity, but the phenyl groups attached to the C2 and N5 position of clofazimine can be replaced by a pyridyl group to provide analogs with improved physicochemical properties and pharmacokinetic characteristics.
A mild and efficient approach for the deprotection of silyl ethers by sodium periodate
TL;DR: In this article, a mild and efficient method for deprotection of silyl ethers is reported, which can be used for a wide range of substrates and is shown to be more efficient than traditional methods.
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Three New Cytotoxic ent-Kaurane Diterpenes from Isodon excisoides.
TL;DR: Three types of ent-kaurane diterpenoids were isolated from the aerial parts of Isodon excisoides to explore the structure-activity relationships of the isolated compounds, and they were tested for their cytotoxic effects against five human cancer cell lines.
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One pot synthesis of dibenzodiazepinones via CuI catalysis in ethylene glycol
TL;DR: This synthetic protocol provides a concise and efficient access to a wide variety of dibenzodiazepinone, including biologically active molecules.
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Research progress in steroidal saponins from the genus Polygonatum: Chemical components, biosynthetic pathways and pharmacological effects.
TL;DR: A review of the chemical constituents of steroidal saponins from Polygonatum, including their structural characteristics, possible biosynthetic pathways and pharmacological effects is provided in this article .
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