Chuanlun Sheng
Jilin University
8 Papers
Chuanlun Sheng is an academic researcher from Jilin University. The author has contributed to research in topics: Inflammation & microRNA. The author has an hindex of 3, co-authored 7 publications.
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Papers
Identification of a Novel Eight-lncRNA Prognostic Signature for HBV-HCC and Analysis of Their Functions Based on Coexpression and ceRNA Networks.
TL;DR: In conclusion, this study identified a novel eight-lncRNA prognosis signature for HBV-HCC patients and these lncRNAs may be potential therapeutic targets.
EV71 virus reduces Nrf2 activation to promote production of reactive oxygen species in infected cells
TL;DR: Evaluating the role of the Keap1–Nrf2 pathway in modulating apoptosis and inflammatory reactions triggered by oxidative stress in Vero and RD cells upon EV71 infection found it can trigger ROS production, cell death, andinflammatory reactions by modulating the Nrf2 and Keap 1 levels of infected cells.
Integrated analysis of lncRNA-associated ceRNA network reveals potential biomarkers for the prognosis of hepatitis B virus-related hepatocellular carcinoma.
TL;DR: The LINC00346-miR-10a-5p-CDK1 axis may be an important mechanism for HBV-related HCC, and genes in this ceRNAaxis may be potential prognostic biomarkers and therapeutic targets.
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M1 Macrophage-Derived Exosomal MicroRNA-326 Suppresses Hepatocellular Carcinoma Cell Progression Via Mediating NF-κB Signaling Pathway.
TL;DR: M1 macrophages-derived exosomal miR-326 suppresses proliferation, migration and invasion as well as advances apoptosis of HCC through down-regulating NF-κB expression.
The NK-1R Antagonist Aprepitant Prevents LPS-Induced Oxidative Stress and Inflammation in RAW264.7 Macrophages.
TL;DR: It is shown that aprepitant protects macrophages against oxidative stress by reducing the generation of ROS and the expression of NOX-4 and inhibits the secretion of pro-inflammatory cytokines and chemotactic factors by mediating the NF-κB signaling pathway.