The invention discloses a polypeptide composition for detecting a serum marker of an autoimmune disease patient and an application of the polypeptide composition and belongs to the technical field of medicines. Polypeptide with bonding capability on the serum marker of an autoimmune disease is screened out from a phage random peptide library, and is applied to immunological detection of the serum marker through artificial synthesis. The polypeptide composition comprises all or partial sequences as shown in SEQID NO.1-19. In addition, the invention further discloses a chip comprising the polypeptide composition, an enzyme-linked immune response plate and a kit. The obtained polypeptide sequences have good bonding capability on the serum marker of the autoimmune disease patient, and can be applied to diagnosis and evaluation of the autoimmune disease.

Polypeptide composition for detecting serum marker of autoimmune disease patient and application of polypeptide composition

The invention discloses an epitope of rheumatoid arthritis and application thereof, belonging to the technical field of immunologic diagnosis. The epitope is a polypeptide, and the amino acid sequence is disclosed as SEQ ID NO:1 in the sequence table. ELISA detection and patient serum reaction condition indicate that the epitope polypeptide can be specifically combined with IgG in the patient serum, and does not react with the serum of a health person. The epitope polypeptide can be used for preparing medicines for diagnosing rheumatoid arthritis.

Epitope of rheumatoid arthritis and application thereof

The invention discloses an epitope of systemic lupus erythematosus and an application thereof, belonging to the technical field of immunology diagnosis. The epitope is a polypeptide of which the amino acid sequence is shown as a sequence table SEQ ID NO:1. As proved by ELISA (Enzyme-Linked Immunosorbent Assay) detection and the serum reaction condition of a patient, the epitope polypeptide can be specifically combined with IgG (Immunoglobulin G) in the serum of the patient without reacting with the serum of a healthy person. The epitope polypeptide can be used for preparing a medicament for diagnosing systemic lupus erythematosus.

Epitope of systemic lupus erythematosus and application thereof

The invention discloses an epitope for sicca syndrome and application thereof, and belongs to the technical field of immunological diagnosis. The epitope is a polypeptide, and an amino acid sequence of the epitope is shown as SEQ ID NO: 1. The epitope is the polypeptide, and enzyme-linked immunosorbent assay (ELISA) detection and the reaction condition of the blood serum of patients indicate that the epitope can be combined with immunoglobulin G (IgG) in the blood serum of the patients specifically and is not reacted with healthy blood. The epitope polypeptide can be used for preparing medicines for diagnosing sicca syndrome.

Epitope for sicca syndrome and application thereof

The invention relates to a polypeptide, a detector containing the polypeptide, and a detection kit containing the polypeptide. The polypeptide is composed of an amino acid sequence represented by the SEQ ID No.1. The polypeptide, the detector containing the polypeptide, and the detection kit containing the polypeptide are useful in the diagnosis of sicca syndrome.

Polypeptide, detector containing the polypeptide, and detection kit containing the polypeptide

Secondary sicca syndrome epitope and application thereof

The invention provides a novel polypeptide which is applicable to the diagnosis of systemic lupus erythematosus. An IgG antibody of the polypeptide antigen has very high sensitivity and specificity in the diagnosis of systemic lupus erythematosus.

Application of novel polypeptide in diagnosis of systemic lupus erythematosus

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