Christopher Staley
University of Minnesota
149 Papers
370 Citations
Christopher Staley is an academic researcher from University of Minnesota. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 35, co-authored 131 publications. Previous affiliations of Christopher Staley include Biotechnology Institute & University of South Florida.
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Papers
Microbial source tracking markers for detection of fecal contamination in environmental waters: relationships between pathogens and human health outcomes
Valerie J. Harwood,Christopher Staley,Christopher Staley,Brian D. Badgley,Kim Borges,Asja Korajkic +5 more
TL;DR: An integrated understanding of the advantages and drawbacks of the many MST methods targeting human sources advanced over the past several decades will benefit managers, regulators, researchers, and other users of this rapidly growing area of environmental microbiology.
661
Effect of Fecal Microbiota Transplantation on Recurrence in Multiply Recurrent Clostridium difficile Infection: A Randomized Trial.
Colleen R. Kelly,Alexander Khoruts,Christopher Staley,Michael J. Sadowsky,Mortadha Abd,Mustafa Alani,Brianna Bakow,Patrizia Curran,Joyce McKenney,Allison Tisch,Steven E. Reinert,Jason T. Machan,Lawrence J. Brandt +12 more
TL;DR: A double-blind, randomized, controlled study of colonoscopic FMT for treatment of recurrent CDI, with results suggesting that colonoscopic delivery has advantages in terms of efficacy, safety, and patient acceptance and tolerability compared with administration via the nasoenteric route.
563
Interaction of gut microbiota with bile acid metabolism and its influence on disease states.
TL;DR: The current understanding of the interactions between the gut microbial community, bile acid biotransformation, and disease states is highlighted, and future directions to better understand these complex associations are addressed.
Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.
Christopher Smillie,Christopher Smillie,Jenny Sauk,Dirk Gevers,Jonathan Friedman,Jaeyun Sung,Jaeyun Sung,Ilan Youngster,Ilan Youngster,Elizabeth L. Hohmann,Christopher Staley,Alexander Khoruts,Michael J. Sadowsky,Jessica R. Allegretti,Mark Smith,Ramnik J. Xavier,Eric J. Alm +16 more
TL;DR: A statistical model is built that predicts which bacterial species will engraft in a given host, and a method to infer strain genotypes and track them over time is developed, finding that engraftment can be predicted largely from the abundance and phylogeny of bacteria in the donor and the pre-FMT patient.
364
Application of Illumina next-generation sequencing to characterize the bacterial community of the Upper Mississippi River
Christopher Staley,Tatsuya Unno,Trevor J. Gould,B. D. W. Jarvis,Jane Phillips,James B. Cotner,Michael J. Sadowsky +6 more
TL;DR: A next‐generation, Illumina‐based sequencing approach was used to characterize the bacterial community at ten sites along the Upper Mississippi River to evaluate shifts in the community potentially resulting from upstream inputs and land use changes.
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