Christopher Santarlas
2 Papers
Christopher Santarlas is an academic researcher. The author has contributed to research in topics: Immunology & Autoimmunity. The author has an hindex of 1, co-authored 1 publications.
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Papers
Monogenic Early-Onset Lymphoproliferation and Autoimmunity: The Natural History of STAT3 GOF Syndrome.
Jennifer W. Leiding,Tiphanie P. Vogel,Valentine G.J. Santarlas,Rahul Mhaskar,Madison R. Smith,Alexandre F. Carisey,Alexander Vargas-Hernández,Manuel Silva-Carmona,Maximilian Heeg,Anne Rensing-Ehl,Bénédicte Neven,Jérôme Hadjadj,Sophie Hambleton,Timothy Ronan Leahy,Martin van Hagen,Charlotte Cunningham-Rundles,Cullen M. Dutmer,Svetlana O. Sharapova,Mervi Taskinen,Ignatius Chua,Rosie Hague,Christian Klemann,Larysa Kostyuchenko,Tomohiro Morio,Akaluck Thatayatikom,Ahmet Ozen,Anna Scherbina,Cindy S. Bauer,Sarah E. Flanagan,Eleonora Gambineri,Lisa Giovannini-Chami,Jennifer Heimall,Kathleen E. Sullivan,Eric J. Allenspach,Neil Romberg,Sean Deane,Benjamin T Prince,Melissa J. Rose,John Bohnsack,Talal Mousallem,Rohith Jesudas,Maria Marluce dos Santos Vilela,Michael O'Sullivan,Jana Pachlopnik Schmid,Stepanka Pruhova,Matthew Rees,Helen C. Su,Sami L. Bahna,Safa Baris,Lisa M. Bartnikas,Amy Chang Berger,Tracy A Briggs,S. Brothers,Vanessa Bundy,Alice Y. Chan,Shanmuganathan Chandrakasan,Mette Christiansen,Theresa Cole,Matthew C. Cook,Mukesh Desai,Ute Fischer,David A. Fulcher,Silvanna Gallo,A. Gauthier,Andrew R. Gennery,José G. Marques,Frédéric Gottrand,Bodo Grimbacher,Eyal Grunebaum,Emma Haapaniemi,Sari Hämäläinen,Kaarina Heiskanen,Tarja Heiskanen-Kosma,Hal M. Hoffman,Luis Ignacio Gonzalez-Granado,A. L. Guerreiro,Leena Kainulainen,Ashish R Kumar,Monica G. Lawrence,Carina Levin,Timi Martelius,Olaf Neth,Peter Olbrich,Alejandro Palma,Niraj C. Patel,Tamara C Pozos,Kahn Preece,Saul Oswaldo Lugo Reyes,M.A. Russell,Yael Dinur Schejter,Christine M. Seroogy,Jan Sinclair,Effie Skevofilax,Dan Suan,Daniel Suegeorgz,Paul Szabolcs,Helena Fleck Velasco,Klaus Warnatz,Kelly Walkovich,Austen Worth,Mikko Seppänen,Troy R. Torgerson,Georgios Sogkas,Stephan Ehl,Stuart G. Tangye,Megan A. Cooper,Joshua D. Miller,Lisa R Forbes Satter,Svetlana Aleshkevich,Luis M. Allende,T. Prescott Atkinson,Faranaz Atschekzei,Sezin Aydemir,Utku Aygunes,Vincent Barlogis,Ulrich Baumann,John Belko,Liliana Bezrodnik,Ariane Biebl,Lori Broderick,Nancy Bunin,María Soledad Caldirola,Martin Castelle,Fatih Celmeli,Louis-Marie Charbonnier,Talal A. Chatila,Deepak Chellapandian,Haluk Cokugras,Niall Conlon,Fionnuala Cox,Etienne Crickx,Buket Dalgic,Virgil A. S. H. Dalm,Silvia Danielian,Nerea Domínguez-Pinilla,Tal Dujovny,Mikael Ebbo,Ahmet Eken,Brittany Esty,Alexandre Fabre,Alain Fischer,Mark C. Hannibal,Laura A. Huppert,Marc D. Ikeda,Stephen Jolles,Kent W. Jolly,Neil Jones,Musa Kakakukcu,Maria Kanariou,Elif Karakoc-Aydiner,Theoni Karamantziani,Charikleia Kelaidi,M. J. Keogan,Ayşenur Paç Kısaarslan,Ayca Kiykim,Adam Klocperk,Kosmas Kotsonis,Natalia B. Kuzmenko,Sylvie Leroy,Harry Lesmana,D. Lianou,Hilary Longhurst,Myriam Ricarda Lorenz,Patrick Maffucci,Ania Manson,Sarah Marchal,Marion Malphettes,L. F. Marega,Andrea A. Mauracher,Kornvalee Meesilpavikai,Holly K. Miller,Joy Mombourquette,Noel G. Morgan,Anna Mukhina,Aladjidi Nathalie,Brigitte Nelken,David Nolan,Anna-Carin Norlin,Matías Oleastro,Alper Ozcan,Marlène Pasquet,José R.M. Pegler,Capucine Picard,Sophia Polychronopoulou,Pierre Quartier,Jan Ramakers,Katrina L. Randall,V. Koneti Rao,Allison Sarah Remiker,Géraldine Resin,Peter Richmond,Frédéric Rieux-Laucat,Yulia Rodina,Pierre-Simon Rohrlich,John Sachs,Inga S. Sakovich,Christopher Santarlas,Sinan Sari,Gregory S. Sawicki,Uwe Dr. Schauer,Selma Cecilia Scheffler Mendoza,Oksana Schvetz,Reinhold E. Schmidt,Klaus Schwarz,Anna Sediva,Kyle James Sinclair,Mary Slatter,John W. Sleasman,Katerina Stergiou,Narissara Suratannon,Kayo Tanita,Grace Thompson,Stephen Travis,Timothy David Trojan,Maria Tsinti,Ekrem Unal,Luciano Urdinez,Felisa Vázquez-Gómez,Maria del Carmen Garcia Villa,Michael Weinrich,Mitchell J. Weiss,B. Wright,Ebru Yilmaz,Radana Zachova,Juan F. Quesada +224 more
TL;DR: In this paper , the authors defined the scope, natural history, treatment, and overall survival of a large global cohort of patients with pathogenic STAT3 gain-of-function (GOF) variants.
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NADPH Oxidase 2-Derived Reactive Oxygen Species Promote CD8+ T Cell Effector Function.
Jing Chen,Chao Liu,Anna V. Chernatynskaya,Brittney Newby,Todd M. Brusko,Yuan Xu,Jessie Barra,Nadine N. Morgan,Christopher Santarlas,Westley H. Reeves,Hubert M. Tse,Jennifer W. Leiding,Clayton E. Mathews +12 more
TL;DR: It is identified that superoxide generated by NOX2 must be converted into hydrogen peroxide to transduce the redox signal in CD8+ T cells and indicated that NOX2 plays a nonredundant role in TCR-mediated CD8+ T cell effector function.