Christopher Ferrante
Rutgers University
8 Papers
48 Citations
Christopher Ferrante is an academic researcher from Rutgers University. The author has contributed to research in topics: Ryanodine receptor & Calcium signaling. The author has an hindex of 7, co-authored 8 publications.
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Papers
The Adenosine-Dependent Angiogenic Switch of Macrophages to an M2-Like Phenotype is Independent of Interleukin-4 Receptor Alpha (IL-4Rα) Signaling
Christopher Ferrante,Grace Pinhal-Enfield,Genie Elson,Bruce N. Cronstein,György Haskó,Shalini Outram,Samuel Leibovich +6 more
TL;DR: Adenosine signaling suppresses the TLR-dependent expression of TNF-α, IL-12, IFN-γ, and several other inflammatory cytokines by macrophages and induces the expression of vascular endothelial growth factor (VEGF) and IL-10.
336
Recombinant MG53 Protein Modulates Therapeutic Cell Membrane Repair in Treatment of Muscular Dystrophy
Noah Weisleder,Norio Takizawa,Pei-Hui Lin,Xianhua Wang,Chun-Mei Cao,Yan Zhang,Tao Tan,Christopher Ferrante,Hua Zhu,Pin-Jung Chen,Rosalie Yan,Matthew Sterling,Xiaoli Zhao,Moonsun Hwang,Miyuki Takeshima,Chuanxi Cai,Heping Cheng,Hiroshi Takeshima,Rui-Ping Xiao,Jianjie Ma +19 more
TL;DR: The data support the concept of targeted cell membrane repair in regenerative medicine, and present MG53 protein as an attractive biological reagent for restoration of membrane repair defects in human diseases.
208
TRIC channels are essential for Ca2+ handling in intracellular stores.
Masayuki Yazawa,Christopher Ferrante,Jue Feng,Kazuhiro Mio,Toshihiko Ogura,Toshihiko Ogura,Miao Zhang,Miao Zhang,Pei-Hui Lin,Zui Pan,Shinji Komazaki,Kazuhiro Kato,Miyuki Nishi,Miyuki Nishi,Xiaoli Zhao,Noah Weisleder,Chikara Sato,Jianjie Ma,Hiroshi Takeshima,Hiroshi Takeshima +19 more
TL;DR: Two TRIC (trimeric intracellular cation) channel subtypes are reported that are differentially expressed on intrACEllular stores in animal cell types and are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intrace cellular stores.
169
Type 1 Inositol (1,4,5)-Trisphosphate Receptor Activates Ryanodine Receptor 1 to Mediate Calcium Spark Signaling in Adult Mammalian Skeletal Muscle
Andoria Tjondrokoesoemo,Na Li,Na Li,Pei-Hui Lin,Pei-Hui Lin,Zui Pan,Zui Pan,Christopher Ferrante,Natalia Shirokova,Marco Brotto,Noah Weisleder,Noah Weisleder,Jianjie Ma,Jianjie Ma +13 more
TL;DR: This work shows that onset of these spatially confined Ca2+ sparks involves interaction between activation of IP3R and RyR near the sarcolemmal membrane, and indicates that membrane-delimited signaling involving cross-talk between IP3r1 and Ryr1 contributes to Ca2- spark activation in skeletal muscle.
31
Systemic ablation of RyR3 alters Ca2+ spark signaling in adult skeletal muscle
Noah Weisleder,Christopher Ferrante,Yutaka Hirata,Claude Collet,Yi Chu,Heping Cheng,Hiroshi Takeshima,Jianjie Ma +7 more
TL;DR: Kinetic analysis reveals that systemic ablation of RyR3 results in significant changes to the initiation, duration and amplitude of individual Ca2+ sparks in muscle fibers, which may reflect the adaptation of the muscleCa2+ signaling or contractile machinery due to the loss ofRyR3 expression in distal tissues.
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