Christopher Farley
Whitman College
6 Papers
13 Citations
Christopher Farley is an academic researcher from Whitman College. The author has contributed to research in topics: Catalysis & Nucleophile. The author has an hindex of 3, co-authored 4 publications.
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Papers
Improved reproducibility of unit-cell parameters in macromolecular cryocrystallography by limiting dehydration during crystal mounting
TL;DR: Unit-cell reproducibility is improved by maintaining the humidity of crystals during cryomounting, which improves the quality of unit-cell photosynthesis.
Efficient cryoprotection of macromolecular crystals using vapor diffusion of volatile alcohols.
TL;DR: Effective for several different protein crystals, the approach obviates the need for liquid soaking and opens up a heretofore underutilized class of cryoprotective agents for macromolecular crystallography.
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Amination of Nitro-Substituted Heteroarenes by Nucleophilic Substitution of Hydrogen.
Michael Mandler,Nina Suss,Antonio Ramirez,Christopher Farley,Darpandeep Aulakh,Yeheng Zhu,Sarah C. Traeger,Amy Narducci Sarjeant,Merrill L. Davies,Bruce A. Ellsworth,Alicia Regueiro-Ren +10 more
TL;DR: In this paper , an open-air method for the transition metal-free direct amination of nitro(hetero)arenes by anilines is disclosed, where an aromatic C-H bond is substituted via oxidative nucleophilic aromatic substitution of hydrogen (ONSH).
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The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order.
Douglas H. Juers,Christopher Farley,C.P. Saxby,R.A. Cotter,Jackson K. B. Cahn,K. Harrison,Z. Wu +6 more
TL;DR: Cryosolution thermal contraction is found to have an impact on cryocooled protein and unit-cell volumes and conformations and in some cases, its adjustment can produce higher quality diffraction data.
Synthesis of Bicyclo[1.1.0]butanes from Iodo-Bicyclo[1.1.1]pentanes.
Michael Mandler,James Mignone,Elizabeth A. Jurica,Maximilian D. Palkowitz,Darpandeep Aulakh,Anthony N. Cauley,Christopher Farley,Shasha Zhang,Sarah C. Traeger,Amy Narducci Sarjeant,Bruce A. Ellsworth,Alicia Regueiro-Ren +11 more
TL;DR: In this article , a photo-Hunsdiecker reaction was used to synthesize substituted bicyclo[1.1.0] butanes under metal-free conditions at room temperature.
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