Disclosed herein are methods for determining the copy number of a chromosome in a fetus in the context of non-invasive prenatal diagnosis. In an embodiment, the measured genetic data from a sample of genetic material that contains both fetal DNA and maternal DNA is analyzed, along with the genetic data from the biological parents of the fetus, and the copy number of the chromosome of interest is determined. In an embodiment, the maternal serum is measured using a single-nucleotide polymorphism (SNP) microarray, along with parental genomic data, and the determination of the chromosome copy number is used to make clinical decisions pertaining to the fetus.

Methods for non-invasive prenatal ploidy calling

Computer-implemented systems and methods are disclosed for providing a tagging interface for tagging external content In accordance with some embodiments, a method is provided for tagging content external to a database system The method comprises accessing the external content via a web browser of an electronic device The method also comprises enhancing the web browser by providing a tagging interface for tagging at least a portion of the external content The method further comprises receiving created tag associated with a tagged portion of the external document content, and exporting the external content and the received tag to the database system The tagging interface can also provide an option to export the created tag to an internal database system

Systems and methods for providing a tagging interface for external content

Computer-implemented systems and methods are disclosed for comparing and associating objects. In some embodiments, a method is provided for associating a first object with one or more objects within a plurality of objects, each object comprising a first plurality of properties, each property comprising data reflecting a characteristic of an entity represented by the object, the associated objects comprising matching data in corresponding properties for a second plurality of properties. The method may include executing, for each object within the plurality of objects and for the first object, the following: creating a slug for the object, the slug comprising the second plurality of properties from the object; and inputting the slug for the object into a Bloom filter. Further, the method may include creating for a bin within the Bloom filter corresponding to the slug for the first object, an association between objects whose slugs correspond to the bin if the slugs for those objects match.

Computer-implemented systems and methods for comparing and associating objects

Systems and methods are provided for analyzing entity performance In accordance with one implementation, a method is provided that includes receiving data associated with a geographic region and transforming the received data into an object model The method also includes analyzing the object model to associate the received data with a plurality of entities and to associate the received data with a plurality of sub-geographic regions of the geographic region The method also includes applying a prediction model to the plurality of sub-geographic regions using the object model to determine a predicted performance for at least one entity of the plurality of entities Further, the method includes determining actual performance for the at least one entity and providing a user interface that includes information associated with the predicted performance, the actual performance, or a combination of the predicted performance and the actual performance

Systems and methods for analyzing performance of an entity

Systems and methods are provided for analyzing entity performance. In one implementation, a method is provided that includes receiving a request with one or more filter selections and accessing a data structure comprising a plurality of categories of information showing interactions associated with multiple entities. The method also comprises identifying a set of categories of the plurality of categories within the data structure based on the one or more filter selections. The method further comprises processing the information of the identified categories to analyze a performance of one or more entities of the multiple entities in accordance with the one or more filter selections and providing the processed information to display the performance of the one or more entities on a user interface.

Methods and systems for analyzing entity performance

The system described herein enables clinicians and researchers to use aggregated genetic and phenotypic data from clinical trials and medical records to make the safest, most effective treatment decisions for each patient. This involves (i) the creation of a standardized ontology for genetic, phenotypic, clinical, pharmacokinetic, pharmacodynamic and other data sets, (ii) the creation of a translation engine to integrate heterogeneous data sets into a database using the standardized ontology, and (iii) the development of statistical methods to perform data validation and outcome prediction with the integrated data. The system is designed to interface with patient electronic medical records (EMRs) in hospitals and laboratories to extract a particular patient's relevant data. The system may also be used in the context of generating phenotypic predictions and enhanced medical laboratory reports for treating clinicians. The system may also be used in the context of leveraging the huge amount of data created in medical and pharmaceutical clinical trials. The ontology and validation rules are designed to be flexible so as to accommodate a disparate set of clients. The system is also designed to be flexible so that it can change to accommodate scientific progress and remain optimally configured.

System and method for integrating and validating genotypic, phenotypic and medical information into a database according to a standardized ontology

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System and method for integrating and validating genotypic, phenotypic and medical information into a database according to a standardized ontology