Christopher A. Moskaluk
University of Virginia
201 Papers
1.7K Citations
Christopher A. Moskaluk is an academic researcher from University of Virginia. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 60, co-authored 191 publications. Previous affiliations of Christopher A. Moskaluk include University of Virginia Health System & National Institutes of Health.
Chat about Author
Papers
•Journal Article
Molecular Classification of Human Carcinomas by Use of Gene Expression Signatures
Andrew I. Su,John B. Welsh,Lisa M. Sapinoso,Suzanne G. Kern,Petre Dimitrov,Hilmar Lapp,Peter G. Schultz,Steven M. Powell,Christopher A. Moskaluk,Henry F. Frierson,Garret M. Hampton +10 more
TL;DR: This study demonstrates the feasibility of predicting the tissue origin of a carcinoma in the context of multiple cancer classes by accurately and confidently predicting the anatomical site of tumor origin for 90% of 175 carcinomas, including 9 of 12 metastatic lesions.
790
Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum
John B. Welsh,Lisa M. Sapinoso,Suzanne G. Kern,David Brown,Tao Liu,Asne R. Bauskin,Robyn L. Ward,Nicholas J. Hawkins,David I. Quinn,Pamela J. Russell,Robert L. Sutherland,Samuel N. Breit,Christopher A. Moskaluk,Henry F. Frierson,Garret M. Hampton +14 more
TL;DR: The results suggest that the combination of annotation/protein sequence analysis, transcript profiling, immunohistochemistry, and immunoassay is a powerful approach for delineating candidate biomarkers with potential clinical significance and may be broadly applicable to other human diseases.
514
Whole Slide Imaging Versus Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter Blinded Randomized Noninferiority Study of 1992 Cases (Pivotal Study).
Sanjay Mukhopadhyay,Michael Feldman,Esther Abels,Raheela Ashfaq,Senda Beltaifa,Nicolas G. Cacciabeve,Helen P. Cathro,Liang Cheng,Kumarasen Cooper,Glenn E. Dickey,Ryan M. Gill,Robert P. Heaton,René Kerstens,Guy Lindberg,Reenu Malhotra,James Mandell,Ellen D. Manlucu,Anne M. Mills,Stacey E. Mills,Christopher A. Moskaluk,Mischa E. T. Nelis,Deepa T. Patil,Christopher G. Przybycin,Jordan P. Reynolds,Brian P. Rubin,Mohammad H. Saboorian,Mauricio Salicru,Mark A. Samols,Charles D. Sturgis,Kevin Turner,Mark R. Wick,Ji Y. Yoon,Po Zhao,Clive R. Taylor +33 more
TL;DR: It is concluded that WSI is noninferior to microscopy for primary diagnosis in surgical pathology, including biopsies and resections stained with hematoxylin and eosin, immunohistochemistry and special stains, valid across a wide variety of organ systems and specimen types.
Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms.
Louis B. Brill,William A. Kanner,André Fehr,Ywonne Andrén,Christopher A. Moskaluk,Thomas Löning,Göran Stenman,Henry F. Frierson +7 more
TL;DR: The studies show that MYB activation through gene fusion or other mechanisms is a major oncogenic event in adenoid cystic carcinoma occurring at various anatomic sites, and that neoplasms sometimes in the differential diagnosis are also labeled.
347
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma
Yotam Drier,Yotam Drier,Yotam Drier,Matthew J. Cotton,Matthew J. Cotton,Matthew J. Cotton,Kaylyn E. Williamson,Kaylyn E. Williamson,Kaylyn E. Williamson,Shawn M. Gillespie,Shawn M. Gillespie,Shawn M. Gillespie,Russell J.H. Ryan,Russell J.H. Ryan,Russell J.H. Ryan,Michael J. Kluk,Christopher D. Carey,Scott J. Rodig,Lynette M. Sholl,A. Afrogheh,William C. Faquin,Lurdes Queimado,Jun Qi,Michael J. Wick,Adel K. El-Naggar,James E. Bradner,James E. Bradner,Christopher A. Moskaluk,Jon C. Aster,Birgit Knoechel,Birgit Knoechel,Bradley E. Bernstein,Bradley E. Bernstein,Bradley E. Bernstein +33 more
TL;DR: This study identifies super-enhancer translocations that drive MYB expression and provides insight into downstream MYB functions in alternate ACC lineages.