Christophe Moreno
Université libre de Bruxelles
281 Papers
1.9K Citations
Christophe Moreno is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Medicine & Hepatitis C. The author has an hindex of 53, co-authored 259 publications. Previous affiliations of Christophe Moreno include Free University of Brussels & University of Toronto.
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Papers
Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis
Joan Clària,Richard Moreau,François Fenaille,Alex Amoros,Christophe Junot,Henning Grønbæk,Minneke J. Coenraad,Alain Pruvost,Aurélie Ghettas,Emeline Chu-Van,Cristina López-Vicario,Karl Oettl,Paolo Caraceni,Carlo Alessandria,Jonel Trebicka,Jonel Trebicka,Marco Pavesi,Carme Deulofeu,Agustín Albillos,Thierry Gustot,Tania M. Welzel,Javier Fernández,Rudolf E. Stauber,Faouzi Saliba,Noémie Butin,Benoit Colsch,Christophe Moreno,François Durand,Frederik Nevens,Rafael Bañares,Daniel Benten,Pere Ginès,Alexander L. Gerbes,Rajiv Jalan,Paolo Angeli,Mauro Bernardi,Vicente Arroyo +36 more
TL;DR: Serum KP activity was normal in compensated cirrhosis, increased in AD and further increased in ACLf, in parallel with SI; it was remarkably higher in ACLF with kidney failure than in ACLFs without kidney failure in the absence of differences in urine KP activity and fractional excretion of KP metabolites.
94
Impact of insulin resistance on sustained response in HCV patients treated with pegylated interferon and ribavirin: A meta-analysis
Pierre Deltenre,Alexandre Louvet,Maud Lemoine,Abbas Mourad,Laetitia Fartoux,Christophe Moreno,Jean Henrion,Philippe Mathurin,Lawrence Serfaty,Lawrence Serfaty +9 more
TL;DR: HCV patients with IR have a 20% lower SVR than patients without IR, and the baseline HOMA-IR index is a major determinant of SVR.
88
Efficacy and safety of simeprevir with PegIFN/ribavirin in naïve or experienced patients infected with chronic HCV genotype 4.
Christophe Moreno,Christophe Hézode,Patrick Marcellin,Suzanne Bourgeois,Sven Francque,Didier Samuel,Fabien Zoulim,Jean-Didier Grangé,Umesh Shukla,Oliver Lenz,Sivi Ouwerkerk-Mahadevan,Bart Fevery,Monika Peeters,Maria Beumont,W. Jessner +14 more
TL;DR: Efficacy and safety of SMV 150mg QD for 12 weeks with PR in treatment-naïve or -experienced patients with chronic HCV GT4 infection were in line with previous reports for HCVGT1 infection.
87
PNPLA3 (rs738409 C>G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis.
Eric Trepo,Erwan Guyot,Nathalie Ganne-Carrié,Delphine Degre,Thierry Gustot,Denis Franchimont,Angela Sutton,Pierre Nahon,Christophe Moreno +8 more
TL;DR: The remarkable observation that rs738409 confers higher risk of HCC in CHC and ALD warrants additional replication and may well illustrate gene-host interactions and indicate that the influence of PNPLA3 on chronic liver disease heritability could go far beyond a mere impact on steatosis.
83
Liver transplantation for alcoholic hepatitis: A systematic review with meta-analysis.
TL;DR: The percentage of alcohol relapse of AH transplanted patients is similar than that of patients who underwent elective liver transplantation, and 14% of patients with clinically severe AH have alcohol relapse after liver transplation.