Christophe Moreno
Université libre de Bruxelles
281 Papers
1.9K Citations
Christophe Moreno is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Medicine & Hepatitis C. The author has an hindex of 53, co-authored 259 publications. Previous affiliations of Christophe Moreno include Free University of Brussels & University of Toronto.
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Papers
The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseases
Michael Adler,Béatrice Gulbis,Christophe Moreno,Sylvie Evrard,Gontran Verset,Philippe Golstein,Brigitte Frotscher,Nathalie Nagy,Philippe Thiry +8 more
TL;DR: Comparisons of the diagnostic accuracy using AUROCs of the 5 biochemical scores in the HCV population and global series of patients with chronic liver disease reinforce the last recommendations of the HAS, which equally ranked the following methods for the diagnosis of liver cirrhosis: liver biopsy, Fibroscan, and FibroTest.
103
CCR5 Deficiency Exacerbates T-Cell–Mediated Hepatitis in Mice
Christophe Moreno,Thierry Gustot,Charles Nicaise,Eric Quertinmont,Nathalie Nagy,Marc Parmentier,Olivier Le Moine,Jacques Devière,Hubert Louis +8 more
TL;DR: CCR5 deficiency exacerbates T‐cell–mediated hepatitis, and leads to increased levels of C CR5 ligands and a more pronounced liver mononuclear infiltrate, suggesting that CCR5 expression can modulate severity of immunomediated liver injury.
103
Sepsis in alcohol-related liver disease
Thierry Gustot,Javier Fernández,Gyongyi Szabo,Agustín Albillos,Alexandre Louvet,Rajiv Jalan,Richard Moreau,Christophe Moreno +7 more
TL;DR: The aim of the present study is to review the current knowledge of infectious complications in ALD and its pathophysiological mechanisms, distinguishing the role of alcohol consumption and the contribution of different forms of ALD.
98
Identification of 19 Novel Hepatitis C Virus Subtypes-Further Expanding HCV Classification.
Charlotte Hedskog,Bandita Parhy,Silvia Chang,Stefan Zeuzem,Christophe Moreno,Stephen D. Shafran,Sergio Borgia,Tarik Asselah,Laurent Alric,Armando Abergel,Jyh Jou Chen,Jane Collier,Dharmesh Kapoor,Robert H. Hyland,Peter Simmonds,Hongmei Mo,Evguenia S. Svarovskaia +16 more
TL;DR: Nineteen novel HCV subtypes were identified, suggesting an even greater genetic diversity of HCVSubtypes than previously recognized, and the impact of subtypes on treatment outcome is investigated.
98
A 17-Beta-Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease
Jiecheng Yang,Eric Trepo,Pierre Nahon,Pierre Nahon,Qian Cao,Christophe Moreno,Eric Letouzé,Sandrine Imbeaud,Quentin Bayard,Thierry Gustot,Jacques Devière,Paulette Bioulac-Sage,J. Calderaro,Nathalie Ganne-Carrié,Nathalie Ganne-Carrié,Alexis Laurent,Jean-Frédéric Blanc,Erwan Guyot,Angela Sutton,Marianne Ziol,Marianne Ziol,Jessica Zucman-Rossi,J.-C. Nault,J.-C. Nault +23 more
TL;DR: The HSD17B13 rs72613567 loss of function variant is protective of HCC development in patients with ALD, and the proportion of TA allele carriers with HCC was significantly lower than in CLD patients without HCC, even after adjustment for age, sex, and fibrosis.
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